日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions

神经退行性疾病中靶向小胶质细胞的生物标志物和治疗策略:现状与未来方向

Noh, Min-Young; Kwon, Hyuk Sung; Kwon, Min-Soo; Nahm, Minyeop; Jin, Hee Kyung; Bae, Jae-Sung; Kim, Seung Hyun

Mutations in NEK1 cause ciliary dysfunction as a novel pathogenic mechanism in amyotrophic lateral sclerosis.

NEK1 基因突变导致纤毛功能障碍,这是肌萎缩侧索硬化症的一种新的致病机制

Noh Min-Young, Oh Seong-Il, Kim Young-Eun, Cha Sun Joo, Sung Wonjae, Oh Ki-Wook, Park Yurim, Mun Ji Young, Ki Chang-Seok, Nahm Minyeop, Kim Seung Hyun

Graphene Quantum Dots Attenuate TDP-43 Proteinopathy in Amyotrophic Lateral Sclerosis

石墨烯量子点可减轻肌萎缩侧索硬化症中的TDP-43蛋白病变

Park, Na Young; Heo, Yunseok; Yang, Ji Won; Yoo, Je Min; Jang, Hye Ji; Jo, Ju Hee; Park, Su Jeong; Lin, Yuxi; Choi, Joonhyeok; Jeon, Hyeonjin; Cha, Sun Joo; Bae, Gaeun; Kim, Donghoon; Kim, Juhee; Zeno, Wade; Park, Jong Bo; Isozumi, Noriyoshi; Saio, Tomohide; Kim, Seung Hyun; Lee, Hojae; Hong, Byung Hee; Nahm, Minyeop; Lee, Young-Ho; Hong, Young Bin

Modulation of pain sensitivity by Ascl1- and Lhx6-dependent GABAergic neuronal function in streptozotocin diabetic mice

链脲佐菌素糖尿病小鼠中 Ascl1 和 Lhx6 依赖性 GABA 能神经元功能对疼痛敏感性的调节

Sung-Min Hwang, Md Mahbubur Rahman, Eun Jin Go, Jueun Roh, Rayoung Park, Sung-Gwon Lee, Minyeop Nahm, Temugin Berta, Yong Ho Kim, Chul-Kyu Park

miRNA-214 to predict progression and survival in ALS

miRNA-214可用于预测ALS的进展和生存期。

Noh, Min-Young; Kwon, Min-Soo; Oh, Ki-Wook; Nahm, Minyeop; Park, Jinseok; Jin, Hee Kyung; Bae, Jae-Sung; Son, Bugyeong; Kim, Seung Hyun

Microglial lipid droplets as therapeutic targets in age-related neurodegenerative diseases

小胶质细胞脂滴作为年龄相关神经退行性疾病的治疗靶点

Sung, Soyoung; Kim, Hui-Ju; Cha, Sun Joo; Nahm, Minyeop; Kim, Seung Hyun; Kwon, Min-Soo

Emerging role of senescent microglia in brain aging-related neurodegenerative diseases

衰老小胶质细胞在脑衰老相关神经退行性疾病中的新兴作用

Rim, Chan; You, Min-Jung; Nahm, Minyeop; Kwon, Min-Soo

Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia

前颗粒蛋白单倍体不足介导人类小胶质细胞中细胞质 TDP-43 聚集和溶酶体异常

Wonjae Sung #, Min-Young Noh #, Minyeop Nahm, Yong Sung Kim, Chang-Seok Ki, Young-Eun Kim, Hee-Jin Kim, Seung Hyun Kim

Role of NCKAP1 in the Defective Phagocytic Function of Microglia-Like Cells Derived from Rapidly Progressing Sporadic ALS

NCKAP1 在快速进展型散发性 ALS 衍生的小胶质细胞样细胞吞噬功能缺陷中的作用

Min-Young Noh #, Min-Soo Kwon #, Ki-Wook Oh, Minyeop Nahm, Jinseok Park, Young-Eun Kim, Chang-Seok Ki, Hee Kyung Jin, Jae-Sung Bae, Seung Hyun Kim

Proteostasis and Ribostasis Impairment as Common Cell Death Mechanisms in Neurodegenerative Diseases

蛋白质稳态和核糖体稳态受损是神经退行性疾病中常见的细胞死亡机制

Lim, Su Min; Nahm, Minyeop; Kim, Seung Hyun