日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Final outcomes analysis of the cell product SQZ-PBMC-HPV Phase 1 trial in incurable HPV16+ solid tumors shows improved overall survival in patients with increased CD8+ T cell tumor infiltration

针对无法治愈的HPV16阳性实体瘤,细胞产品SQZ-PBMC-HPV的I期临床试验最终结果分析显示,CD8+ T细胞肿瘤浸润增加的患者总生存期有所改善。

Weaver, Alice N; Iams, Wade T; Park, Jong Chul; Mita, Monica; Holtick, Udo; Gordon, Michael S; Rodabaugh, Kerry J; Dhani, Neesha; Neupane, Prakash; Taylor, Matthew; Amanda Duvall, E; Jennings, Julia; Miselis, Nathan R; Loughhead, Scott; Warren, Marshelle S; Bernstein, Howard; Klussmann, Jens P; Baranda, Joaquina; Jimeno, Antonio

Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors

一项旨在确定自体外周血单核细胞经修饰可呈递 HPV16 抗原 (SQZ-PBMC-HPV) 在 HLA-A*02+ HPV16+ 实体瘤患者中的安全性和剂量的 1 期研究

Jimeno, Antonio; Baranda, Joaquina; Iams, Wade T; Park, Jong Chul; Mita, Monica; Gordon, Michael S; Taylor, Matthew; Dhani, Neesha; Leal, Alexis D; Neupane, Prakash; Eng, Cathy; Yeku, Oladapo; Mita, Alain; Moser, Justin C; Butler, Marcus; Loughhead, Scott M; Jennings, Julia; Miselis, Nathan R; Ji, Rui-Ru; Nair, Nitya; Kornacker, Martin; Zwirtes, Ricardo F; Bernstein, Howard; Sharei, Armon

Technology Literacy in Undergraduate Medical Education: Review and Survey of the US Medical School Innovation and Technology Programs

本科医学教育中的技术素养:美国医学院创新与技术项目的回顾与调查

Wang, Judy Jiaqi; Singh, Rishabh K; Miselis, Heather Hough; Stapleton, Stephanie Nicole

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

口服 ERK1/2 抑制剂 MK-8353 的开发,用于治疗晚期实体肿瘤患者

Stergios J Moschos, Ryan J Sullivan, Wen-Jen Hwu, Ramesh K Ramanathan, Alex A Adjei, Peter C Fong, Ronnie Shapira-Frommer, Hussein A Tawbi, Joseph Rubino, Thomas S Rush 3rd, Da Zhang, Nathan R Miselis, Ahmed A Samatar, Patrick Chun, Eric H Rubin, James Schiller, Brian J Long, Priya Dayananth, Donna

MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis

实体肿瘤中的 MCL1 和 BCL-xL 水平可预测 dinaciclib 诱导的细胞凋亡

Robert N Booher, Harold Hatch, Brian M Dolinski, Thi Nguyen, Lauren Harmonay, Ali-Samer Al-Assaad, Mark Ayers, Michael Nebozhyn, Andrey Loboda, Heather A Hirsch, Theresa Zhang, Bin Shi, Carrie E Merkel, Minilik H Angagaw, Yaolin Wang, Brian J Long, Xianlu Q Lennon, Nathan Miselis, Vincenzo Pucci, Ja

Unique functions of CHK1 and WEE1 underlie synergistic anti-tumor activity upon pharmacologic inhibition

CHK1 和 WEE1 的独特功能是药物抑制后产生协同抗肿瘤活性的基础

Amy D Guertin, Melissa M Martin, Brian Roberts, Melissa Hurd, Xianlu Qu, Nathan R Miselis, Yaping Liu, Jing Li, Igor Feldman, Yair Benita, Andrew Bloecher, Carlo Toniatti, Stuart D Shumway

Biopersistence and potential adverse health impacts of fibrous nanomaterials: what have we learned from asbestos?

纤维纳米材料的生物持久性和潜在的健康不良影响:我们从石棉中学到了什么?

Sanchez, Vanesa C; Pietruska, Jodie R; Miselis, Nathan R; Hurt, Robert H; Kane, Agnes B

Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis

弓形虫诱导人成纤维细胞分泌粒细胞集落刺激因子和粒细胞-巨噬细胞集落刺激因子:对中性粒细胞凋亡的影响

Channon, Jacqueline Y; Miselis, Kristin A; Minns, Laurie A; Dutta, Chaitali; Kasper, Lloyd H

Central neuronal circuit innervating the lordosis-producing muscles defined by transneuronal transport of pseudorabies virus

支配产生脊柱前凸的肌肉的中枢神经回路,由伪狂犬病毒的跨神经元运输所定义

Daniels, D; Miselis, R R; Flanagan-Cato, L M

Retrograde, transneuronal spread of pseudorabies virus in defined neuronal circuitry of the rat brain is facilitated by gE mutations that reduce virulence

在鼠脑特定神经回路中,伪狂犬病毒的逆行性跨神经元传播是由降低毒力的gE突变促进的。

Yang, M; Card, J P; Tirabassi, R S; Miselis, R R; Enquist, L W