5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells.
5hmC 增强 PARP 捕获并恢复对化疗耐药的 BRCA1/2 缺陷细胞的 PARP 抑制剂敏感性
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110393
Kharat Suhas S, Mishra Arun P, Sengodan Satheesh K, Dierman Dillon, Fox Stephen D, Chazin Walter J, Sharan Shyam K