Small Molecule Activators of the Mitochondrial Protease ClpP Induce Senescence in Triple-Negative Breast Cancer Cells and Sensitize Cells to the Bcl-2 Inhibitor Venetoclax
线粒体蛋白酶ClpP的小分子激活剂可诱导三阴性乳腺癌细胞衰老，并使细胞对Bcl-2抑制剂维奈托克敏感。
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影响因子:
doi:10.21203/rs.3.rs-7682325/v1
Daglish, Sabrina C D; Canterbury, Owen G; Graves, Paul R; Carter, Sarah A; Beese, Sydney M; Hynek, Maggie A; Mouery, Brandon L; Mistreanu, Andrei J; Bhatt, Aadra P; Tellez, Nestor; Butler, Mitchell T; Aponte-Collazo, Lucas J; Fennell, Emily M J; Herring, Laura E; Lyons, Scott; Mills, C Allie; Ashamalla, Hani; Iwanowicz, Edwin J; Morris, John P 4th; Bear, James E; Greer, Yoshimi Endo; Lipkowitz, Stanley; Graves, Lee M
Bcl-2
肿瘤
肿瘤免疫
Senescence
细胞衰老
乳腺癌
线粒体
衰老
细胞生物学
