日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cell cycle inhibitors activate the hypoxia-induced DDX41/STING pathway to mediate antitumor immune response in liver cancer

细胞周期抑制剂激活缺氧诱导的DDX41/STING通路，从而介导肝癌中的抗肿瘤免疫反应。

期刊:JCI Insight
影响因子:6.3
doi:10.1172/jci.insight.170532
Po Yee Wong ，Cerise Yuen Ki Chan ，Helen Do Gai Xue ，Chi Ching Goh ，Jacinth Wing Sum Cheu ，Aki Pui Wah Tse ，Misty Shuo Zhang ，Yan Zhang ，Carmen Chak Lui Wong
DDX4
免疫/内分泌
细胞生物学
STING
肿瘤
信号转导
肿瘤免疫
肝癌
发表日期：2024
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Polo-like kinase 4 inhibitor CFI-400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity

Polo 样激酶 4 抑制剂 CFI-400945 通过扰动细胞周期和引发抗肿瘤免疫来抑制肝癌

期刊:Hepatology
影响因子:12.9
doi:10.1002/hep.32461
Cerise Yuen-Ki Chan, Vincent Wai-Hin Yuen, David Kung-Chun Chiu, Chi-Ching Goh, Kelsie L Thu, David W Cescon, Isabel Soria-Bretones, Cheuk-Ting Law, Jacinth Wing-Sum Cheu, Derek Lee, Aki Pui-Wah Tse, Kel Vin Tan, Misty Shuo Zhang, Bowie Po-Yee Wong, Chun-Ming Wong, Pek-Lan Khong, Irene Oi-Lin Ng, Ma
肿瘤
肝癌
其它细胞
发表日期：2023
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Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development

缺氧诱导因子调节腺苷代谢促进肝癌发展

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.ade5111
Jacinth Wing-Sum Cheu, David Kung-Chun Chiu, Kenneth Kin-Leung Kwan, Chunxue Yang, Vincent Wai-Hin Yuen, Chi Ching Goh, Noreen Nog-Qin Chui, Wei Shen, Cheuk-Ting Law, Qidong Li, Misty Shuo Zhang, Macus Hao-Ran Bao, Bowie Po-Yee Wong, Cerise Yuen-Ki Chan, Cindy Xinqi Liu, Grace Fu-Wan Sit, Zher Yee O
代谢
肿瘤
肝癌
发表日期：2023
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Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer

铁死亡抑制蛋白1抑制促进肝癌肿瘤铁死亡和抗肿瘤免疫反应

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2023.03.001
Jacinth Wing-Sum Cheu ，Derek Lee ，Qidong Li ，Chi Ching Goh ，Macus Hao-Ran Bao ，Vincent Wai-Hin Yuen ，Misty Shuo Zhang ，Chunxue Yang ，Cerise Yuen-Ki Chan ，Aki Pui-Wah Tse ，Grace Fu-Wan Sit ，Cindy Xinqi Liu ，Irene Oi-Lin Ng ，Chun-Ming Wong ，Carmen Chak-Lui Wong
肿瘤
铁死亡
免疫/内分泌
肿瘤免疫
肝癌
发表日期：2023
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Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

缺氧诱导的巨胞饮作用是肝癌的一种代谢途径。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-28618-9
Misty Shuo Zhang ，Jane Di Cui ，Derek Lee ，Vincent Wai-Hin Yuen ，David Kung-Chun Chiu ，Chi Ching Goh ，Jacinth Wing-Sum Cheu ，Aki Pui-Wah Tse ，Macus Hao-Ran Bao ，Bowie Po Yee Wong ，Carrie Yiling Chen ，Chun-Ming Wong ，Irene Oi-Lin Ng ，Carmen Chak-Lui Wong
代谢
肝癌
肿瘤
肿瘤免疫
发表日期：2022
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CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma

CFI-402257 是一种 TTK 抑制剂，可有效抑制肝细胞癌。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2119514119
Chan, Cerise Yuen-Ki; Chiu, David Kung-Chun; Yuen, Vincent Wai-Hin; Law, Cheuk-Ting; Wong, Bowie Po-Yee; Thu, Kelsie Lynn; Cescon, David Ward; Soria-Bretones, Isabel; Cheu, Jacinth Wing-Sum; Lee, Derek; Tse, Aki Pui-Wah; Zhang, Misty Shuo; Tan, Kel Vin; Ng, Irene Oi-Lin; Khong, Pek-Lan; Yau, Thomas Chung-Cheung; Bray, Mark Robert; Mak, Tak Wah; Wong, Carmen Chak-Lui
细胞生物学
肿瘤
TTK
肿瘤免疫
发表日期：2022
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Inhibition of CMTM4 Sensitizes Cholangiocarcinoma and Hepatocellular Carcinoma to T Cell-Mediated Antitumor Immunity Through PD-L1

CMTM4抑制通过PD-L1增强胆管癌和肝细胞癌对T细胞介导的抗肿瘤免疫的敏感性

期刊:Hepatology Communications
影响因子:4.6
doi:10.1002/hep4.1682
Chui, Noreen Nog-Qin; Cheu, Jacinth Wing-Sum; Yuen, Vincent Wai-Hin; Chiu, David Kung-Chun; Goh, Chi-Ching; Lee, Derek; Zhang, Misty Shuo; Ng, Irene Oi-Lin; Wong, Carmen Chak-Lui
肿瘤
T细胞
肿瘤免疫
PD-L1
T细胞
胆管癌
细胞生物学
CMTM4
免疫/内分泌
发表日期：2022
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Genome-Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment

全基因组 CRISPR/Cas9 文库筛选显示，限制谷氨酰胺的饮食与抑制丙酮酸代谢相结合可有效治疗肝癌

期刊:Advanced Science
影响因子:
doi:10.1002/advs.202202104
Chunxue Yang, Derek Lee, Misty Shuo Zhang, Aki Pui-Wah Tse, Lai Wei, Macus Hao-Ran Bao, Bowie Po-Yee Wong, Cerise Yuen-Ki Chan, Vincent Wai-Hin Yuen, Yiling Chen, Carmen Chak-Lui Wong
代谢
肿瘤
肝癌
WB
发表日期：2022
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Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer

全基因组 CRISPR-Cas9 敲除文库筛选发现心磷脂合成中的 PTPMT1 对肝癌在缺氧条件下生存至关重要

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2020.108676
Macus Hao-Ran Bao, Chunxue Yang, Aki Pui-Wah Tse, Lai Wei, Derek Lee, Misty Shuo Zhang, Chi Ching Goh, David Kung-Chun Chiu, Vincent Wai-Hin Yuen, Cheuk-Ting Law, Wai-Ching Chin, Noreen Nog-Qin Chui, Bowie Po-Yee Wong, Cerise Yuen-Ki Chan, Irene Oi-Lin Ng, Clive Yik-Sham Chung, Chun-Ming Wong, Carme
肿瘤
肝癌
发表日期：2021
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Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

全基因组 CRISPR/Cas9 文库筛选发现 PHGDH 是 HCC 中索拉非尼耐药的关键驱动因素

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-019-12606-7
Lai Wei, Derek Lee, Cheuk-Ting Law, Misty Shuo Zhang, Jialing Shen, Don Wai-Ching Chin, Allen Zhang, Felice Ho-Ching Tsang, Ceci Lok-Sze Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong, Chun-Ming Wong
信号转导
发表日期：2019
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