Mitani Shohei相关文献与解析，生知库 | 链接生命科学的每一步

Cysteine protease cathepsin B promotes high population density-induced mutagenesis, driving genome evolution and competitive growth in response to the crowding stress

半胱氨酸蛋白酶组织蛋白酶B促进高密度种群诱导的突变，从而驱动基因组进化和竞争性生长，以应对拥挤压力。

doi:10.64898/2025.12.22.696062

Yu, Bin; Suehiro, Yuji; Johnson, Bryan J; Lee, Eui-Seung; Li, Dongdong; Huang, Yawen; Johnson, Joshua; Ou, Guangshuo; DeGregori, James; Mitani, Shohei; Xue, Ding

发表日期：2025

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AMPK-FOXO-IP3R signaling pathway mediates neurological and developmental defects caused by mitochondrial DNA mutations

AMPK-FOXO-IP3R信号通路介导线粒体DNA突变引起的神经系统和发育缺陷

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2302490120

Zhang, Hu; Zhu, Yunan; Suehiro, Yuji; Mitani, Shohei; Xue, Ding

Febuxostat ameliorates muscle degeneration and movement disorder of the dystrophin mutant model in Caenorhabditis elegans

非布司他可改善秀丽隐杆线虫肌营养不良蛋白突变模型的肌肉退化和运动障碍

期刊:Journal of Physiological Sciences

影响因子:3.2

doi:10.1186/s12576-023-00888-y

Yoshina, Sawako; Izuhara, Luna; Mashima, Rei; Maejima, Yuka; Kamatani, Naoyuki; Mitani, Shohei

C. elegans

发表日期：2023

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A humanized Caenorhabditis elegans model for studying pathogenic mutations in VPS45, a protein essential for membrane trafficking, associated with severe congenital neutropenia

利用人源化秀丽隐杆线虫模型研究VPS45（一种对膜转运至关重要的蛋白质）的致病突变，该突变与严重的先天性中性粒细胞减少症相关。

期刊:microPublication Biology

影响因子:

doi:10.17912/micropub.biology.001052

Gengyo-Ando, Keiko; Tateyama, Minoru; Mitani, Shohei; Ando, Hideki; Nakai, Junichi

The transcription factor unc-130/FOXD3/4 contributes to the biphasic calcium response required to optimize avoidance behavior

转录因子unc-130/FOXD3/4参与了优化回避行为所需的双相钙反应。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-022-05942-0

Hori, Sayaka; Mitani, Shohei

发表日期：2022

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Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals

通过对DNA损伤反应缺陷动物进行诱变，高效收集大量突变体。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-021-87226-7

Suehiro, Yuji; Yoshina, Sawako; Motohashi, Tomoko; Iwata, Satoru; Dejima, Katsufumi; Mitani, Shohei

毒理研究

发表日期：2021

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UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase is indispensable for oogenesis, oocyte-to-embryo transition, and larval development of the nematode Caenorhabditis elegans

UDP-N-乙酰氨基葡萄糖-多萜磷酸N-乙酰氨基葡萄糖磷酸转移酶对于线虫秀丽隐杆线虫的卵子发生、卵母细胞向胚胎的转变以及幼虫发育是必不可少的

期刊:Glycobiology

影响因子:3.3

doi:10.1093/glycob/cwy104

Kanaki, Nanako; Matsuda, Ayako; Dejima, Katsufumi; Murata, Daisuke; Nomura, Kazuko H; Ohkura, Takashi; Gengyo-Ando, Keiko; Yoshina, Sawako; Mitani, Shohei; Nomura, Kazuya

The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans

小GTP酶ARF-1.2是秀丽隐杆线虫单细胞管状结构形成的调节因子。

期刊:Journal of Physiological Sciences

影响因子:3.2

doi:10.1007/s12576-018-0617-5

Kage-Nakadai, Eriko; Sun, Simo; Iwata, Satoru; Yoshina, Sawako; Nishikawa, Yoshikazu; Mitani, Shohei

OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses

中间神经元的OFF反应通过电突触，根据刺激强度优化回避行为。

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1007477

Hori, Sayaka; Oda, Shigekazu; Suehiro, Yuji; Iino, Yuichi; Mitani, Shohei

神经科学

发表日期：2018

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Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans

EGO-1和RRF-1在秀丽隐杆线虫生殖系外泌RNAi效率调控中的双重作用

Cysteine protease cathepsin B promotes high population density-induced mutagenesis, driving genome evolution and competitive growth in response to the crowding stress

半胱氨酸蛋白酶组织蛋白酶B促进高密度种群诱导的突变，从而驱动基因组进化和竞争性生长，以应对拥挤压力。

AMPK-FOXO-IP3R signaling pathway mediates neurological and developmental defects caused by mitochondrial DNA mutations

AMPK-FOXO-IP3R信号通路介导线粒体DNA突变引起的神经系统和发育缺陷

Febuxostat ameliorates muscle degeneration and movement disorder of the dystrophin mutant model in Caenorhabditis elegans

非布司他可改善秀丽隐杆线虫肌营养不良蛋白突变模型的肌肉退化和运动障碍

A humanized Caenorhabditis elegans model for studying pathogenic mutations in VPS45, a protein essential for membrane trafficking, associated with severe congenital neutropenia

利用人源化秀丽隐杆线虫模型研究VPS45（一种对膜转运至关重要的蛋白质）的致病突变，该突变与严重的先天性中性粒细胞减少症相关。

The transcription factor unc-130/FOXD3/4 contributes to the biphasic calcium response required to optimize avoidance behavior

转录因子unc-130/FOXD3/4参与了优化回避行为所需的双相钙反应。

Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals

通过对DNA损伤反应缺陷动物进行诱变，高效收集大量突变体。

UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase is indispensable for oogenesis, oocyte-to-embryo transition, and larval development of the nematode Caenorhabditis elegans

UDP-N-乙酰氨基葡萄糖-多萜磷酸N-乙酰氨基葡萄糖磷酸转移酶对于线虫秀丽隐杆线虫的卵子发生、卵母细胞向胚胎的转变以及幼虫发育是必不可少的

The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans

小GTP酶ARF-1.2是秀丽隐杆线虫单细胞管状结构形成的调节因子。

OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses

中间神经元的OFF反应通过电突触，根据刺激强度优化回避行为。