A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.
全基因组 CRISPR-Cas9 筛选发现氨基酸转运蛋白 SLC43A1 (LAT3) 是结直肠癌细胞对奥沙利铂敏感性的主要决定因素
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doi:10.1101/2025.04.21.649594
Pawar N R, Wade H M, Jackson Z, Poungpeth N, Mitchell A V, Jewell C P, Chan D, Robey R W, Batista P J, Jenkins L M, Gottesman M M
