日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Non-redundant roles of the phosphoinositide phosphatases PTEN and PIPP in PI3K/AKT signaling in breast cancer.

磷脂酰肌醇磷酸酶 PTEN 和 PIPP 在乳腺癌 PI3K/AKT 信号传导中发挥着不可替代的作用。

Ooms Lisa M, Ferguson Daniel T, Rodgers Samuel J, Sukhija Karmanpreet K, Jones Emily I, Csolle Mariah P, Yip Hon Yan Kelvin, Daly Roger J, Tiganis Tony, McLean Catriona A, Papa Antonella, Mitchell Christina A

Autophagic lysosome reformation in health and disease

自噬溶酶体在健康和疾病中的重塑

Nanayakkara, Randini; Gurung, Rajendra; Rodgers, Samuel J; Eramo, Matthew J; Ramm, Georg; Mitchell, Christina A; McGrath, Meagan J

The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer

乳腺癌中 1A 类 PI3K 和 Wnt/β-catenin 偶联信号传导的机制

Rodgers, Samuel J; Mitchell, Christina A; Ooms, Lisa M

Defective lysosome reformation during autophagy causes skeletal muscle disease

自噬过程中溶酶体重塑缺陷会导致骨骼肌疾病

McGrath, Meagan J; Eramo, Matthew J; Gurung, Rajendra; Sriratana, Absorn; Gehrig, Stefan M; Lynch, Gordon S; Lourdes, Sonia Raveena; Koentgen, Frank; Feeney, Sandra J; Lazarou, Michael; McLean, Catriona A; Mitchell, Christina A

A late endosome signaling hub that couples PI3Kα and WNT/β-catenin signaling in breast cancer

乳腺癌中连接PI3Kα和WNT/β-catenin信号通路的晚期内体信号枢纽

Rodgers, Samuel J; Hamila, Sabryn A; Mitchell, Christina A; Ooms, Lisa M

TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers

TCPTP 调控 SFK 和 STAT3 信号通路,并在三阴性乳腺癌中缺失。

Shields, Benjamin J; Wiede, Florian; Gurzov, Esteban N; Wee, Kenneth; Hauser, Christine; Zhu, Hong-Jian; Molloy, Timothy J; O'Toole, Sandra A; Daly, Roger J; Sutherland, Robert L; Mitchell, Christina A; McLean, Catriona A; Tiganis, Tony

Autophosphorylation of serine 608 in the p85 regulatory subunit of wild type or cancer-associated mutants of phosphoinositide 3-kinase does not affect its lipid kinase activity

野生型或癌症相关突变型磷脂酰肌醇3-激酶p85调节亚基中丝氨酸608的自磷酸化不影响其脂质激酶活性。

Layton, Meredith J; Saad, Mirette; Church, Nicole L; Pearson, Richard B; Mitchell, Christina A; Phillips, Wayne A

Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeleton

死亡结构域沉默因子(SODD)抑制骨骼肌和肾脏富集的肌醇5-磷酸酶(SKIP),并调节磷脂酰肌醇3-激酶(PI3K)/Akt信号通路对肌动蛋白细胞骨架的影响。

Rahman, Parvin; Huysmans, Richard D; Wiradjaja, Fenny; Gurung, Rajendra; Ooms, Lisa M; Sheffield, David A; Dyson, Jennifer M; Layton, Meredith J; Sriratana, Absorn; Takada, Hidetoshi; Tiganis, Tony; Mitchell, Christina A

Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes

鉴定出 P-Rex1 是一种新型 Rac1-鸟嘌呤核苷酸交换因子 (GEF),可促进脂肪细胞中的肌动蛋白重塑和 GLUT4 蛋白运输

Balamatsias, Demis; Kong, Anne M; Waters, Joanne E; Sriratana, Absorn; Gurung, Rajendra; Bailey, Charles G; Rasko, John E J; Tiganis, Tony; Macaulay, S Lance; Mitchell, Christina A

Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)•collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.

鉴定出一种富含脯氨酸的肌醇多磷酸 5-磷酸酶 (PIPP) • 塌陷反应介质蛋白 2 (CRMP2) 复合物,该复合物调节神经突的延伸

Astle Megan V, Ooms Lisa M, Cole Adam R, Binge Lauren C, Dyson Jennifer M, Layton Meredith J, Petratos Steven, Sutherland Calum, Mitchell Christina A