日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrative epigenetics and transcriptomics identify aging genes in human blood

整合表观遗传学和转录组学鉴定人类血液中的衰老基因

Moqri, Mahdi; Ying, Kejun; Poganik, Jesse R; Herzog, Chiara; Chen, Qingwen; Emamifar, Mehrnoosh; Tyshkovskiy, Alexander; Eames, Alec; Mur, Jure; Glubokov, Dmitrii; Matei-Dediu, Benyamin; Goeminne, Ludger; Mitchell, Wayne; McCartney, Daniel L; Salas, Lucas A; Marioni, Riccardo E; Lasky-Su, Jessica A; Snyder, Michael P; Gladyshev, Vadim N

In Vivo Chemical Reprogramming Is Associated With a Toxic Accumulation of Lipid Droplets Hindering Rejuvenation

体内化学重编程与脂滴毒性积累有关,阻碍细胞再生

Mitchell, Wayne; de Magalhães, Cecília G; Tyshkovskiy, Alexander; Uchida, Yushi; Goeminne, Ludger J E; Ichimura, Takaharu; Ng, Emery L; Moldakozhayev, Alibek; Bonventre, Joseph V; Gladyshev, Vadim N

The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life.

18S rRNA 甲基转移酶 DIMT-1 在生命后期调节生殖细胞的寿命

Rothi M Hafiz, Sarkar Gautam Chandra, Haddad Joseph Al, Mitchell Wayne, Ying Kejun, Pohl Nancy, Sotomayor-Mena Roberto G, Natale Julia, Dellacona Scarlett, Gladyshev Vadim N, Greer Eric Lieberman

The Mitochondria-Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

靶向线粒体的肽类治疗药物Elamipretide可在不引起组织表观遗传或转录组年龄可检测变化的情况下,改善衰老过程中的心肌和骨骼肌功能。

Mitchell, Wayne; Pharaoh, Gavin; Tyshkovskiy, Alexander; Campbell, Matthew; Marcinek, David J; Gladyshev, Vadim N

In vivo chemical reprogramming is associated with a toxic accumulation of lipid droplets hindering rejuvenation

体内化学重编程与脂滴的毒性积累有关,从而阻碍细胞再生。

Mitchell, Wayne; de Magalhães, Cecília G; Tyshkovskiy, Alexander; Uchida, Yushi; Goeminne, Ludger J E; Ichimura, Takaharu; Ng, Emery L; Bonventre, Joseph V; Gladyshev, Vadim N

Risk of inflammatory bowel disease following hospitalisation with infectious mononucleosis: nationwide cohort study from Denmark

丹麦全国性队列研究:传染性单核细胞增多症住院后发生炎症性肠病的风险

Ebert, Anthony C; Harper, Shania; Vestergaard, Marie V; Mitchell, Wayne; Jess, Tine; Elmahdi, Rahma

Phylogenomics and genetic analysis of solvent-producing Clostridium species

产溶剂梭菌属的系统发育基因组学和遗传分析

Jensen, Rasmus O; Schulz, Frederik; Roux, Simon; Klingeman, Dawn M; Mitchell, Wayne P; Udwary, Daniel; Moraïs, Sarah; Reynoso, Vinicio; Winkler, James; Nagaraju, Shilpa; De Tissera, Sashini; Shapiro, Nicole; Ivanova, Natalia; Reddy, T B K; Mizrahi, Itzhak; Utturkar, Sagar M; Bayer, Edward A; Woyke, Tanja; Mouncey, Nigel J; Jewett, Michael C; Simpson, Séan D; Köpke, Michael; Jones, David T; Brown, Steven D

Perturbations in mitochondrial metabolism associated with defective cardiolipin biosynthesis: An in-organello real-time NMR study

线粒体代谢紊乱与心磷脂生物合成缺陷相关:一项细胞器内实时核磁共振研究

Rua, Antonio J; Mitchell, Wayne; Claypool, Steven M; Alder, Nathan N; Alexandrescu, Andrei T

Disagreement on foundational principles of biological aging

对生物衰老基本原理的分歧

Gladyshev, Vadim N; Anderson, Benjamin; Barlit, Hanna; Barré, Benjamin; Beck, Samuel; Behrouz, Bahareh; Belsky, Daniel W; Chaix, Amandine; Chamoli, Manish; Chen, Brian H; Cheng, Kaiyang; Chuprin, Jane; Churchill, Gary A; Cipriano, Andrea; Colville, Alex; Deelen, Joris; Deigin, Yuri; Edmonds, KeHuan K; English, Bradley W; Fang, Ruogu; Florea, Michael; Gershteyn, Iosif M; Gill, Diljeet; Goetz, Laura H; Gorbunova, Vera; Griffin, Patrick T; Horvath, Steve; Borch Jensen, Martin; Jin, Xin; Jovanovska, Sara; Kajderowicz, Kathrin M; Kasahara, Tomoko; Kerepesi, Csaba; Kulkarni, Subhash; Labunskyy, Vyacheslav M; Levine, Morgan E; Libert, Sergiy; Lu, J Yuyang; Lu, Yuancheng Ryan; Marioni, Riccardo E; McCoy, Brianah M; Mitchell, Wayne; Moqri, Mahdi; Nasirian, Farzaneh; Niimi, Peter; Oh, Hamilton Se-Hwee; Okundaye, Brian; Parkhitko, Andrey A; Peshkin, Leonid; Petljak, Mia; Poganik, Jesse R; Pridham, Glen; Promislow, Daniel E L; Prusisz, Weronika; Quiniou, Margaux; Raj, Ken; Richard, Daniel; Ricon, Jose Luis; Rutledge, Jarod; Scheibye-Knudsen, Morten; Schork, Nicholas J; Seluanov, Andrei; Shadpour, Michael; Shindyapina, Anastasia V; Shuken, Steven R; Sivakumar, Sruthi; Stoeger, Thomas; Sugiura, Ayumu; Sutton, Nadia R; Suvorov, Alexander; Tarkhov, Andrei E; Teeling, Emma C; Trapp, Alexandre; Tyshkovskiy, Alexander; Unfried, Maximilian; Ward-Caviness, Cavin K; Yim, Sun Hee; Ying, Kejun; Yunes, Jeffrey; Zhang, Bohan; Zhavoronkov, Alex

Expanding the synthetic biology toolbox of Cupriavidus necator for establishing fatty acid production.

扩展嗜铜菌合成生物学工具箱,用于建立脂肪酸生产

Mishra Shivangi, Perkovich Paul M, Mitchell Wayne P, Venkataraman Maya, Pfleger Brian F