日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1

桥联苯并氮杂卓酰胺作为RIPK1选择性变构调节剂的发现

Chen, Joanna L; Methot, Joey L; Mitcheltree, Matthew J; Musacchio, Andrew; Corcoran, Emily B; Feng, Guo; Lammens, Alfred; Maskos, Klaus; Palte, Rachel L; Rickard, Meredith M; Otte, Karin M; Mansueto, My S; Venkat, Sriraman; Sondey, Christopher; Thomsen, Maren; Lesburg, Charles A; Fradera, Xavier; Fell, Matthew J; DiMauro, Erin F; Siliphaivanh, Phieng

An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance

一种预先组织好、可与核糖体结合的抗生素能够克服抗菌素耐药性。

Wu, Kelvin J Y; Tresco, Ben I C; Ramkissoon, Antonio; Aleksandrova, Elena V; Syroegin, Egor A; See, Dominic N Y; Liow, Priscilla; Dittemore, Georgia A; Yu, Meiyi; Testolin, Giambattista; Mitcheltree, Matthew J; Liu, Richard Y; Svetlov, Maxim S; Polikanov, Yury S; Myers, Andrew G

A synthetic antibiotic class overcoming bacterial multidrug resistance.

一种能够克服细菌多重耐药性的合成抗生素

Mitcheltree Matthew J, Pisipati Amarnath, Syroegin Egor A, Silvestre Katherine J, Klepacki Dorota, Mason Jeremy D, Terwilliger Daniel W, Testolin Giambattista, Pote Aditya R, Wu Kelvin J Y, Ladley Richard Porter, Chatman Kelly, Mankin Alexander S, Polikanov Yury S, Myers Andrew G

Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors

双环脯氨酸的综合策略:在高效精氨酸酶抑制剂合成中的应用

Li, Derun; Zhang, Hongjun; Lyons, Thomas W; Lu, Min; Achab, Abdelghani; Pu, Qinglin; Childers, Matthew; Mitcheltree, Matthew J; Wang, Jialiang; Martinot, Theodore A; McMinn, Spencer E; Sloman, David L; Palani, Anandan; Beard, Adam; Nogle, Lisa; Gathiaka, Symon; Saurí, Josep; Kim, Hai-Young; Adpressa, Donovon; Spacciapoli, Peter; Miller, J Richard; Palte, Rachel L; Lesburg, Charles A; Cumming, Jared; Fischer, Christian

Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy

发现和优化合理设计的双环人精氨酸酶抑制剂以增强癌症免疫疗法

Mitcheltree, Matthew J; Li, Derun; Achab, Abdelghani; Beard, Adam; Chakravarthy, Kalyan; Cheng, Mangeng; Cho, Hyelim; Eangoor, Padmanabhan; Fan, Peter; Gathiaka, Symon; Kim, Hai-Young; Lesburg, Charles A; Lyons, Thomas W; Martinot, Theodore A; Miller, J Richard; McMinn, Spencer; O'Neil, Jennifer; Palani, Anandan; Palte, Rachel L; Saurí, Josep; Sloman, David L; Zhang, Hongjun; Cumming, Jared N; Fischer, Christian

A practical method for regiocontrolled one-carbon ring contraction

一种区域可控的单碳环收缩的实用方法

Mitcheltree, Matthew J; Konst, Zef A; Herzon, Seth B