日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unrestrained fatty acid oxidation triggers heart failure in mice via cardiolipin loss and mitochondrial dysfunction

不受控制的脂肪酸氧化通过心磷脂丢失和线粒体功能障碍引发小鼠心力衰竭。

Kim, Chai-Wan; Vale, Goncalo; Fu, Xiaorong; McDonald, Jeffrey; Dai, Chongshan; Li, Chao; Wang, Zhao V; Sharma, Gaurav; Khemtong, Chalermchai; Malloy, Craig; Deja, Stanislaw; Burgess, Shawn C; Mitsche, Matthew; Horton, Jay D

Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation.

MBOAT7 低表达是 MASH 的遗传风险因素,它促进了涉及肝细胞 TAZ 上调的促纤维化途径

Moore Mary P, Wang Xiaobo, Kennelly John Paul, Shi Hongxue, Ishino Yuki, Kano Kuniyuki, Aoki Junken, Cherubini Alessandro, Ronzoni Luisa, Guo Xiuqing, Chalasani Naga P, Khalid Shareef, Saleheen Danish, Mitsche Matthew A, Rotter Jerome I, Yates Katherine P, Valenti Luca, Kono Nozomu, Tontonoz Peter, Tabas Ira

Development of Co-Amorphous Systems for Inhalation Therapy-Part 1: From Model Prediction to Clinical Success

用于吸入疗法的共非晶体系的开发——第一部分:从模型预测到临床成功

Fröhlich, Eleonore; Bordoni, Aurora; Mohsenzada, Nila; Mitsche, Stefan; Schröttner, Hartmuth; Zellnitz-Neugebauer, Sarah

Development of Co-Amorphous Systems for Inhalation Therapy-Part 2: In Silico Guided Co-Amorphous Rifampicin-Moxifloxacin and -Ethambutol Formulations

用于吸入疗法的共非晶体系的开发——第二部分:计算机指导的利福平-莫西沙星和-乙胺丁醇共非晶制剂

Fröhlich, Eleonore; Sharafeldin, Noon; Reinisch, Valerie; Mohsenzada, Nila; Mitsche, Stefan; Schröttner, Hartmuth; Zellnitz-Neugebauer, Sarah

Data-Driven Prediction of the Formation of Co-Amorphous Systems

基于数据驱动的共非晶体系形成预测

Fink, Elisabeth; Brunsteiner, Michael; Mitsche, Stefan; Schröttner, Hartmuth; Paudel, Amrit; Zellnitz-Neugebauer, Sarah

Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver

肝脏中 Mboat7 (LPIAT1) 基因缺失会导致 SREBP-1c 激活和脂肪肝

Xia, Mingfeng; Chandrasekaran, Preethi; Rong, Shunxing; Fu, Xiaorong; Mitsche, Matthew A

A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins

药物化学驱动的方法确定甾醇异构酶 EBP 是 TASIN 结直肠癌毒素的分子靶点

Theodoropoulos, Panayotis C; Wang, Wentian; Budhipramono, Albert; Thompson, Bonne M; Madhusudhan, Nikhil; Mitsche, Matthew A; McDonald, Jeffrey G; De Brabander, Jef K; Nijhawan, Deepak

Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress

弧菌利用 2 型分泌脂肪酶将胆固醇与宿主脂肪酸酯化并介导细胞外流

Suneeta Chimalapati #, Marcela de Souza Santos #, Alexander E Lafrance, Ann Ray, Wan-Ru Lee, Giomar Rivera-Cancel, Gonçalo Vale, Krzysztof Pawlowski, Matthew A Mitsche, Jeffrey G McDonald, Jen Liou, Kim Orth

Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice

了解 dysferlin 缺乏小鼠骨骼肌中的脂质积累

Anil K Agarwal, Katie Tunison, Matthew A Mitsche, Jeffrey G McDonald, Abhimanyu Garg

Biotransformation of Scheelite CaWO(4) by the Extreme Thermoacidophile Metallosphaera sedula: Tungsten-Microbial Interface

极端嗜热嗜酸菌Metallosphaera sedula对白钨矿CaWO₄的生物转化:钨-微生物界面

Blazevic, Amir; Albu, Mihaela; Mitsche, Stefan; Rittmann, Simon K-M R; Habler, Gerlinde; Milojevic, Tetyana