日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan

IGF-1 对健康寿命、病理和寿命具有性别二态性、多效性和时间依赖性的影响

期刊:Geroscience
影响因子:5.3
doi:10.1007/s11357-017-9971-0
Nicole M Ashpole, Sreemathi Logan, Andriy Yabluchanskiy, Matthew C Mitschelen, Han Yan, Julie A Farley, Erik L Hodges, Zoltan Ungvari, Anna Csiszar, Sixia Chen, Constantin Georgescu, Gene B Hubbard, Yuji Ikeno, William E Sonntag
信号转导
发表日期：2017
文献求助 收藏

IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms

IGF-1通过性别特异性和时间依赖性机制调节椎骨衰老

期刊:Journal of Bone and Mineral Research
影响因子:5.9
doi:10.1002/jbmr.2689
Ashpole, Nicole M; Herron, Jacquelyn C; Mitschelen, Matthew C; Farley, Julie A; Logan, Sreemathi; Yan, Han; Ungvari, Zoltan; Hodges, Erik L; Csiszar, Anna; Ikeno, Yuji; Humphrey, Mary Beth; Sonntag, William E
IGF-1
衰老
发表日期：2016
文献求助 收藏

IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice

IGF-1 缺乏会损害高血压小鼠的脑肌源性自身调节

期刊:Journal of Cerebral Blood Flow and Metabolism
影响因子:4.9
doi:10.1038/jcbfm.2014.156
Peter Toth, Zsuzsanna Tucsek, Stefano Tarantini, Danuta Sosnowska, Tripti Gautam, Matthew Mitschelen, Akos Koller, William E Sonntag, Anna Csiszar, Zoltan Ungvari
心血管
高血压
发表日期：2014
文献求助 收藏

Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat

内皮素-1 诱发的生长激素/IGF-1 缺乏的 Lewis 侏儒大鼠局灶性脑缺血

期刊:Journals of Gerontology Series A-Biological Sciences and Medical Sciences
影响因子:4.3
doi:10.1093/gerona/glu118
Han Yan, Matthew Mitschelen, Peter Toth, Nicole M Ashpole, Julie A Farley, Erik L Hodges, Junie P Warrington, Song Han, Kar-Ming Fung, Anna Csiszar, Zoltan Ungvari, William E Sonntag
IGF-1
Rat
免疫/内分泌
神经科学
发表日期：2014
文献求助 收藏

Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease

衰老过程中的肥胖会加剧小鼠海马中的血脑屏障破坏、神经炎症和氧化应激：对与 β-淀粉样蛋白生成和阿尔茨海默病有关的基因表达的影响

期刊:Journals of Gerontology Series A-Biological Sciences and Medical Sciences
影响因子:4.3
doi:10.1093/gerona/glt177
Zsuzsanna Tucsek, Peter Toth, Danuta Sosnowska, Tripti Gautam, Matthew Mitschelen, Akos Koller, Gabor Szalai, William E Sonntag, Zoltan Ungvari, Anna Csiszar
信号转导
神经
神经炎症
血脑屏障
阿尔茨海默症
Senescence
Goat
发表日期：2014
文献求助 收藏

Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells

脑部放射治疗后，全身性因素导致微血管长期稀疏：内皮祖细胞发挥作用

期刊:American Journal of Physiology-Heart and Circulatory Physiology
影响因子:4.1
doi:10.1152/ajpheart.00308.2014
Ashpole, Nicole M; Warrington, Junie P; Mitschelen, Matthew C; Yan, Han; Sosnowska, Danuta; Gautam, Tripti; Farley, Julie A; Csiszar, Anna; Ungvari, Zoltan; Sonntag, William E
细胞生物学
神经科学
发表日期：2014
文献求助 收藏

Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension

血管紧张素II诱导高血压小鼠的年龄相关性自身调节功能障碍和脑微血管损伤

期刊:Journal of Cerebral Blood Flow and Metabolism
影响因子:4.5
doi:10.1038/jcbfm.2013.143
Toth, Peter; Tucsek, Zsuzsanna; Sosnowska, Danuta; Gautam, Tripti; Mitschelen, Matthew; Tarantini, Stefano; Deak, Ferenc; Koller, Akos; Sonntag, William E; Csiszar, Anna; Ungvari, Zoltan
神经科学
心血管
高血压
发表日期：2013
文献求助 收藏

Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging

肝脏特异性敲低 IGF-1 可通过损害 Nrf2 依赖性抗氧化反应来降低血管氧化应激抵抗力：一种新的血管老化模型

期刊:Journals of Gerontology Series A-Biological Sciences and Medical Sciences
影响因子:4.3
doi:10.1093/gerona/glr164
Lora C Bailey-Downs, Matthew Mitschelen, Danuta Sosnowska, Peter Toth, John T Pinto, Praveen Ballabh, M Noa Valcarcel-Ares, Julie Farley, Akos Koller, Jim C Henthorn, Caroline Bass, William E Sonntag, Zoltan Ungvari, Anna Csiszar
表观遗传
发表日期：2012
文献求助 收藏

Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging.

随着年龄增长，海马体中 MHCI 通路和 PirB 受体的神经胶质表达上调

期刊:Journal of Molecular Neuroscience
影响因子:2.7
doi:10.1007/s12031-012-9783-8
VanGuilder Starkey Heather D, Van Kirk Colleen A, Bixler Georgina V, Imperio Caesar G, Kale Vijay P, Serfass Jacob M, Farley Julie A, Yan Han, Warrington Junie P, Han Song, Mitschelen Matthew, Sonntag William E, Freeman Willard M
神经科学
发表日期：2012
文献求助 收藏

Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia

全脑辐射引起的学习和记忆障碍具有时间敏感性，并且可通过全身性缺氧逆转。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0030444
Warrington, Junie P; Csiszar, Anna; Mitschelen, Matthew; Lee, Yong Woo; Sonntag, William E
神经科学
发表日期：2012
文献求助 收藏