日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Condensins regulate resection-dependent DNA double-strand break repair pathways in replicated chromatin

凝聚蛋白调控复制染色质中依赖于切除的DNA双链断裂修复途径

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkag076
Liu, Mei; Wei, You; Weber, Lisa-Marie; Mladenov, Emil; Lin, Xixi; Mladenova, Veronika; Shafaat, Ramtin Omid; Pantelias, Gabriel E; Gkika, Eleni; Stuschke, Martin; Soni, Aashish; Iliakis, George
信号转导
发表日期：2026
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Evidence for Quasi-High-LET Biological Effects in Clinical Proton Beams That Suppress c-NHEJ and Enhance HR and Alt-EJ.

临床质子束中准高LET生物效应的证据，可抑制c-NHEJ并增强HR和Alt-EJ。

期刊:Cells
影响因子:5.2
doi:10.3390/cells15010086
Mladenov Emil, Pressler Mina, Mladenova Veronika, Soni Aashish, Li Fanghua, Heinzelmann Feline, Esser Johannes Niklas, Hessenow Razan, Gkika Eleni, Jendrossek Verena, Timmermann Beate, Stuschke Martin, Iliakis George
发表日期：2026
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Radiation Dose-Dependent and -Independent Pulmonary Infiltrates in Patients with High-Grade Pneumonitis After Radiochemotherapy and Durvalumab Consolidation for Stage III NSCLC

III期非小细胞肺癌患者接受放化疗和度伐利尤单抗巩固治疗后出现高级别肺炎，其肺部浸润的放射剂量依赖性和非依赖性分析

期刊:Diagnostics
影响因子:3.3
doi:10.3390/diagnostics16060827
Herz, Andreas; Khouya, Aymane; Guberina, Maja; Metzenmacher, Martin; Opitz, Marcel; Pöttgen, Christoph; Fischedick, Gerrit; Hautzel, Hubertus; Gauler, Thomas; Herrmann, Ken; Büscher, Erik; Bölükbas, Servet; Doerr, Fabian; Baldes, Natalie; Klüner, Laura Valentina; Schaarschmidt, Benedikt M; Karpf-Wissel, Rüdiger; Winantea, Jane; Bos, Denise; Jendrossek, Verena; Mladenov, Emil; Gockeln, Lena; Hetzel, Mario Andre; Wirsdörfer, Florian; Schuler, Martin; Stuschke, Martin; Guberina, Nika
肺炎
肺癌
肿瘤
肿瘤免疫
细胞生物学
发表日期：2026
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CRISPR/Cas9 generated DSB clusters mimic complex lesions induced by high-LET radiation and shift repair from c-NHEJ to mutagenic repair pathways.

CRISPR/Cas9 生成的 DSB 簇模拟了高 LET 辐射引起的复杂损伤，并将修复从 c-NHEJ 途径转移到诱变修复途径。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-22945-9
Mladenov Emil, Kallies Mathias, Stuschke Martin, Gkika Eleni, Iliakis George
CAS9
发表日期：2025
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The effect of durvalumab consolidation after definitive radiochemotherapy for non-operable stage III non-small cell lung cancer on the dose effect relation for therapy related pulmonary infiltrates as a risk factor for pneumonitis

度伐利尤单抗巩固治疗对不可手术的III期非小细胞肺癌患者在根治性放化疗后，治疗相关性肺浸润作为肺炎危险因素的剂量效应关系的影响

期刊:Translational Lung Cancer Research
影响因子:3.5
doi:10.21037/tlcr-2024-1284
Herz, Andreas; Guberina, Maja; Pöttgen, Christoph; Gauler, Thomas; Ton, That Truong Mike; Fischedick, Gerrit; Kiwitt, Lars Oliver; Lübcke, Wolfgang; Hoffmann, Christian; Schuler, Martin; Metzenmacher, Martin; Schaarschmidt, Benedikt M; Bos, Denise; Opitz, Marcel; Hautzel, Hubertus; Darwiche, Kaid; Bölükbas, Servet; Grapatsas, Konstantinos; Jendrossek, Verena; Gockeln, Lena; Wirsdörfer, Florian; Hetzel, Mario; Mladenov, Emil; Stuschke, Martin; Guberina, Nika
肺炎
肺癌
肿瘤
肿瘤免疫
细胞生物学
发表日期：2025
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Pathologic Complete Response Predicts Long-Term Survival Following Neoadjuvant Induction Chemotherapy and Chemo-Radiotherapy in Stage-III Non-Small Cell Lung Cancer

病理完全缓解可预测III期非小细胞肺癌患者接受新辅助诱导化疗和放化疗后的长期生存率

期刊:Thoracic Cancer
影响因子:2.3
doi:10.1111/1759-7714.70183
Guberina, Maja; Metzenmacher, Martin; Pöttgen, Christoph; Wiesweg, Marcel; Guberina, Nika; Merkel-Jens, Anja; Lütke-Brintrup, Diana; Bölükbas, Servet; Eberhardt, Wilfried E E; Stamatis, Georgios; Doerr, Fabian; Plönes, Till; Hoffmann, Christian; Zaun, Gregor; Höing, Benedikt; Kürten, Cornelius; Mladenov, Emil; Iliakis, George; Kersting, David; Fendler, Wolfgang P; Gauler, Thomas; Opitz, Marcel; Milosevic, Aleksandar; Forsting, Michael; Nensa, Felix; Umutlu, Lale; Funke, Faustina; Hautzel, Hubertus; Herrmann, Ken; Taube, Christian; Theegarten, Dirk; Aigner, Clemens; Schuler, Martin; Stuschke, Martin
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G(2)-Checkpoint Activation in Cells Exposed to Ionizing Radiation

在暴露于电离辐射的细胞中，p38/MK2通路在G(2)检查点激活中作为ATM/ATR下游的Chk1备份发挥作用。

期刊:Cells
影响因子:5.2
doi:10.3390/cells12101387
Luo, Daxian; Mladenov, Emil; Soni, Aashish; Stuschke, Martin; Iliakis, George
Checkpoint
信号转导
ATM
ATR
细胞生物学
发表日期：2023
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New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement

DNA双链断裂修复的新层面：辐射剂量是HR与c-NHEJ参与的关键决定因素

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241914956
Mladenov, Emil; Mladenova, Veronika; Stuschke, Martin; Iliakis, George
发表日期：2023
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Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination

高重组性淋巴母细胞系中基因靶向性的增强并未改变同源重组对DSB的处理。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23169180
Mladenov, Emil; Paul-Konietzko, Katja; Mladenova, Veronika; Stuschke, Martin; Iliakis, George
细胞生物学
发表日期：2022
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PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination

PTEN缺失通过抑制RAD51表达和同源重组增强易错DSB加工和肿瘤细胞放射敏感性

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms232112876
Pei, Xile; Mladenov, Emil; Soni, Aashish; Li, Fanghua; Stuschke, Martin; Iliakis, George
肿瘤
肿瘤免疫
PTEN
RAD51
细胞生物学
肿瘤细胞
发表日期：2022
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