日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Repositioning a Human Kinase Platelet-Derived Growth Factor Receptor Alpha Type II Inhibitor for Malaria and Inhibition of Hemozoin Formation

将人激酶血小板衍生生长因子受体α II型抑制剂重新定位用于疟疾和抑制血红素晶体形成

Mmonwa, Mmakwena M; Audu, Oluwatosin; Maepa, Keletso; Dziwornu, Godwin A; Govender, Preshen; Tshaka, Liso; Burrows, James; Taylor, Dale; Masike, Keabetswe; Njoroge, Mathew; Wicht, Kathryn J; Coulson, Lauren B; Chibale, Kelly

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

ATM激酶抑制剂AZD0156是疟原虫磷脂酰肌醇4-激酶(PI4Kβ)的强效抑制剂,是抗疟药物化学优化的理想候选药物。

Woodland, John G; Coertzen, Dina; Wicht, Kathryn J; Hidalgo, Virginia Franco; Pasaje, Charisse Flerida A; Godoy, Luiz C; Qahash, Tarrick; Mmonwa, Mmakwena M; Dziwornu, Godwin A; Wambua, Lynn; Harries, Sarah; Korkor, Constance M; Njoroge, Mathew; Krugmann, Liezl; Taylor, Dale; Leshabane, Meta; Langeveld, Henrico; Rabie, Tayla; Reader, Janette; van der Watt, Mariëtte; Venter, Nelius; Erlank, Erica; Aswat, Ayesha S; Koekemoer, Lizette L; Yeo, Tomas; Jeon, Jin H; Fidock, David A; Gamo, Francisco Javier; Wittlin, Sergio; Niles, Jacquin C; Llinas, Manuel; Coulson, Lauren B; Birkholtz, Lyn-Marié; Chibale, Kelly

Seascape Genomics of the Smooth Hammerhead Shark Sphyrna zygaena Reveals Regional Adaptive Clinal Variation

平滑双髻鲨(Sphyrna zygaena)的海洋基因组学揭示了区域适应性渐变变异

Grobler, D L; Klein, J D; Dicken, M L; Mmonwa, K; Soekoe, M; van Staden, M; Hagen, S B; Maduna, S N; Bester-van der Merwe, A E

Synthesis, Biological Evaluation and Molecular Docking of Novel Indole-Aminoquinazoline Hybrids for Anticancer Properties

新型吲哚-氨基喹唑啉杂合物的合成、生物学评价及分子对接及其抗癌性能研究

Mphahlele, Malose J; Mmonwa, Mmakwena M; Aro, Abimbola; McGaw, Lyndy J; Choong, Yee Siew

Synthesis and Evaluation of N-(3-Trifluoroacetyl-indol-7-yl) Acetamides for Potential In Vitro Antiplasmodial Properties

N-(3-三氟乙酰基-吲哚-7-基)乙酰胺的合成及体外抗疟原虫特性评估

Malose J Mphahlele, Mmakwena M Mmonwa, Yee Siew Choong

Synthesis and photophysical properties of the 2-(3-(2-Alkyl-6,8-diaryl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)propyl)-6,8-diarylquinazolin-4(3H)-ones

2-(3-(2-烷基-6,8-二芳基-4-氧代-1,2,3,4-四氢喹唑啉-2-基)丙基)-6,8-二芳基喹唑啉-4(3H)-酮的合成及光物理性质

Mmonwa, Mmakwena M; Mphahlele, Malose J; El-Hendawy, Morad M; El-Nahas, Ahmed M; Koga, Nobuaki