日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy

开发并验证首个肾移植术后耐受性共识基因表达特征,并纳入免疫抑制药物治疗的调整。

Christakoudi, Sofia; Runglall, Manohursingh; Mobillo, Paula; Rebollo-Mesa, Irene; Tsui, Tjir-Li; Nova-Lamperti, Estefania; Taube, Catharine; Norris, Sonia; Kamra, Yogesh; Hilton, Rachel; Augustine, Titus; Bhandari, Sunil; Baker, Richard; Berglund, David; Carr, Sue; Game, David; Griffin, Sian; Kalra, Philip A; Lewis, Robert; Mark, Patrick B; Marks, Stephen D; MacPhee, Iain; McKane, William; Mohaupt, Markus G; Paz-Artal, Estela; Kon, Sui Phin; Serón, Daniel; Sinha, Manish D; Tucker, Beatriz; Viklický, Ondrej; Stahl, Daniel; Lechler, Robert I; Lord, Graham M; Hernandez-Fuentes, Maria P

Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples

针对肾移植受者外周血中T细胞介导的排斥反应,开发了一种多变量基因表达特征,并在横断面和纵向样本中进行了验证。

Christakoudi, Sofia; Runglall, Manohursingh; Mobillo, Paula; Tsui, Tjir-Li; Duff, Claire; Domingo-Vila, Clara; Kamra, Yogesh; Delaney, Florence; Montero, Rosa; Spiridou, Anastasia; Kassimatis, Theodoros; Phin-Kon, Sui; Tucker, Beatriz; Farmer, Christopher; Strom, Terry B; Lord, Graham M; Rebollo-Mesa, Irene; Stahl, Daniel; Sacks, Steven; Hernandez-Fuentes, Maria P; Chowdhury, Paramit

Reduced TCR Signaling Contributes to Impaired Th17 Responses in Tolerant Kidney Transplant Recipients

TCR 信号传导减弱导致耐受性肾移植受体的 Th17 反应受损

Estefania Nova-Lamperti, Marco Romano, Sofia Christakoudi, Manohursingh Runglall, Reuben McGregor, Paula Mobillo, Yogesh Kamra, Tjir-Li Tsui, Sonia Norris, Susan John, Dominic A Boardman, Robert I Lechler, Giovanna Lombardi, Maria P Hernandez-Fuentes; www.GAMBITstudy.co.uk

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients

CD40 连接增强和 BCR 信号传导减弱导致耐受性肾移植患者 B 细胞中 IL-10 产生增加

Nova-Lamperti, Estefania; Chana, Prabhjoat; Mobillo, Paula; Runglall, Manohursingh; Kamra, Yogesh; McGregor, Reuben; Lord, Graham M; Lechler, Robert I; Lombardi, Giovanna; Hernandez-Fuentes, Maria P

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

肾移植耐受性的生物标志物:我们预测的是耐受性还是对免疫抑制治疗的反应?

Rebollo-Mesa, I; Nova-Lamperti, E; Mobillo, P; Runglall, M; Christakoudi, S; Norris, S; Smallcombe, N; Kamra, Y; Hilton, R; Bhandari, S; Baker, R; Berglund, D; Carr, S; Game, D; Griffin, S; Kalra, P A; Lewis, R; Mark, P B; Marks, S; Macphee, I; McKane, W; Mohaupt, M G; Pararajasingam, R; Kon, S P; Serón, D; Sinha, M D; Tucker, B; Viklický, O; Lechler, R I; Lord, G M; Hernandez-Fuentes, M P