A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells
一种基于单链可变片段的双特异性T细胞激活抗体，靶向CD117，能够诱导T细胞介导的急性髓系白血病细胞以及造血干细胞和祖细胞的裂解。
期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70055
Volta, Laura; Myburgh, Renier; Hofstetter, Mara; Koch, Christian; Kiefer, Jonathan D; Gobbi, Celeste; Manfredi, Francesco; Zimmermann, Kathrin; Kaufmann, Philipp; Fazio, Serena; Pellegrino, Christian; Russkamp, Norman F; Villars, Danielle; Matasci, Mattia; Maurer, Monique; Mueller, Jan; Schneiter, Florin; Büschl, Paul; Harrer, Niclas; Mock, Jacqueline; Balabanov, Stefan; Nombela-Arrieta, César; Schroeder, Timm; Neri, Dario; Manz, Markus G
发育与干细胞
T细胞
CD117
白血病
T细胞
干细胞
细胞生物学
免疫/内分泌
