Bioinformatic and clinical experimental assay uncovers resistance and susceptibility mechanisms of human glioblastomas to temozolomide and identifies new combined and individual survival biomarkers outperforming MGMT promoter methylation
生物信息学和临床实验分析揭示了人类胶质母细胞瘤对替莫唑胺的耐药和敏感性机制,并鉴定出新的联合和个体生存生物标志物,其性能优于MGMT启动子甲基化。
期刊:Therapeutic Advances in Medical Oncology
影响因子:4.2
doi:10.1177/17588359241292269
Modestov, Alexander; Zolotovskaia, Marianna; Suntsova, Maria; Zakharova, Galina; Seryakov, Aleksander; Jovcevska, Ivana; Mlakar, Jernej; Poddubskaya, Elena; Moisseev, Aleksey; Vykhodtsev, Grigory; Roumiantsev, Sergey; Sorokin, Maksim; Tkachev, Victor; Simonov, Aleksander; Buzdin, Anton