Modlich相关文献与解析，生知库 | 链接生命科学的每一步

Arumugam, Paritha I; Higashimoto, Tomoyasu; Urbinati, Fabrizia; Modlich, Ute; Nestheide, Shawna; Xia, Ping; Fox, Catherine; Corsinotti, Andrea; Baum, Christopher; Malik, Punam; Chang, Timothy H; Nassar, Alexander; Kleinman, Claudia; Bandopadhayay, Pratiti

胶质瘤

衰老

发表日期：2024

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Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 phox -deficient chronic granulomatous disease

将 NCF1 cDNA 靶向敲入 NCF2 基因座可导致 p47 phox 缺陷型慢性肉芽肿病的髓系表型校正

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.5

doi:10.1016/j.omtn.2024.102229

Kah Mun Siow, Merve Güngör, Dominik Wrona, Federica Raimondi, Oleksandr Pastukhov, Panagiotis Tsapogas, Timon Menzi, Michael Schmitz, Péter István Kulcsár, Gerald Schwank, Ansgar Schulz, Martin Jinek, Ute Modlich, Ulrich Siler, Janine Reichenbach

信号转导

发表日期：2024

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Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements

NCF1 基因位点的基因编辑与同源重组和染色体重排有关

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-024-06959-z

Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Michael Schmitz, Katja Bargsten, Lucas Kissling, Daan C Swarts, Geoffroy Andrieux, Toni Cathomen, Ute Modlich, Martin Jinek, Ulrich Siler #, Janine Reichenbach #

信号转导

发表日期：2024

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Lentiviral gene therapy reverts GPIX expression and phenotype in Bernard-Soulier syndrome type C

慢病毒基因治疗可逆转 Bernard-Soulier 综合征 C 型中的 GPIX 表达和表型

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.5

doi:10.1016/j.omtn.2023.06.008

Gonzalo Martinez-Navajas, Jorge Ceron-Hernandez, Iris Simon, Pablo Lupiañez, Sofia Diaz-McLynn, Sonia Perales, Ute Modlich, Jose A Guerrero, Francisco Martin, Teresa Sevivas, Maria L Lozano, Jose Rivera, Veronica Ramos-Mejia, Claudia Tersteeg, Pedro J Real

Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia

大编码序列的表达：毛细血管扩张性共济失调症的基因治疗载体

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-023-46332-4

Tanja Hirch ,Nadine Brander ,Franziska Schenk ,Simon J Pöllmann ,Janine Reichenbach ,Ralf Schubert ,Ute Modlich

基因治疗

发表日期：2023

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Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output

型流感病毒感染指示造血向巨核细胞谱系输出

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2022.111447

Marcel G E Rommel, Lisa Walz, Foteini Fotopoulou, Saskia Kohlscheen, Franziska Schenk, Csaba Miskey, Lacramioara Botezatu, Yvonne Krebs, Iris M Voelker, Kevin Wittwer, Tim Holland-Letz, Zoltán Ivics, Veronika von Messling, Marieke A G Essers, Michael D Milsom, Christian K Pfaller, Ute Modlich

Targeting transgenic proteins to alpha granules for platelet-directed gene therapy

将转基因蛋白靶向 α 颗粒用于血小板定向基因治疗

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.5

doi:10.1016/j.omtn.2021.12.038

Vanessa M A Woods, Lisette J Latorre-Rey, Franziska Schenk, Marcel G E Rommel, Thomas Moritz, Ute Modlich

Understanding the Role of LFA-1 in Leukocyte Adhesion Deficiency Type I (LAD I): Moving towards Inflammation?

了解 LFA-1 在白细胞粘附缺陷 I 型 (LAD I) 中的作用：走向炎症？

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms23073578

Fekadu, Julia; Modlich, Ute; Bader, Peter; Bakhtiar, Shahrzad

炎症/感染

Immunology/Inflammation

Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia

肝窦阻塞综合征及6-硫鸟嘌呤短期应用治疗儿童急性淋巴细胞白血病

期刊:Leukemia

影响因子:13.4

doi:10.1038/s41375-021-01203-7

Stanulla, Martin; Schaeffeler, Elke; Möricke, Anja; Buchmann, Swantje; Zimmermann, Martin; Igel, Svitlana; Schmiegelow, Kjeld; Flotho, Christian; Hartmann, Hans; Illsinger, Sabine; Sauerbrey, Axel; Junk, Stefanie V; Schütte, Peter; Hinze, Laura; Lauten, Melchior; Modlich, Simon; Kolb, Reinhard; Rossig, Claudia; Schwabe, Georg; Gnekow, Astrid K; Fleischhack, Gudrun; Schlegel, Paul Gerhard; Schünemann, Holger J; Kratz, Christian P; Cario, Gunnar; Schrappe, Martin; Schwab, Matthias

Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning

使用基于基因表达的机器学习预测干细胞基因治疗病毒载体的基因毒性

期刊:Molecular Therapy

影响因子:12.1

doi:10.1016/j.ymthe.2021.06.017

Adrian Schwarzer, Steven R Talbot, Anton Selich, Michael Morgan, Juliane W Schott, Oliver Dittrich-Breiholz, Antonella L Bastone, Bettina Weigel, Teng Cheong Ha, Violetta Dziadek, Rik Gijsbers, Adrian J Thrasher, Frank J T Staal, Hubert B Gaspar, Ute Modlich, Axel Schambach, Michael Rothe0

HGG-07. INVESTIGATING THE ROLE OF SENESCENCE IN PEDIATRIC HIGH-GRADE GLIOMAS

HGG-07. 研究衰老在儿童高级别胶质瘤中的作用

Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 phox -deficient chronic granulomatous disease

将 NCF1 cDNA 靶向敲入 NCF2 基因座可导致 p47 phox 缺陷型慢性肉芽肿病的髓系表型校正

Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements

NCF1 基因位点的基因编辑与同源重组和染色体重排有关

Lentiviral gene therapy reverts GPIX expression and phenotype in Bernard-Soulier syndrome type C

慢病毒基因治疗可逆转 Bernard-Soulier 综合征 C 型中的 GPIX 表达和表型

Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia

大编码序列的表达：毛细血管扩张性共济失调症的基因治疗载体

Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output

型流感病毒感染指示造血向巨核细胞谱系输出

Targeting transgenic proteins to alpha granules for platelet-directed gene therapy

将转基因蛋白靶向 α 颗粒用于血小板定向基因治疗

Understanding the Role of LFA-1 in Leukocyte Adhesion Deficiency Type I (LAD I): Moving towards Inflammation?

了解 LFA-1 在白细胞粘附缺陷 I 型 (LAD I) 中的作用：走向炎症？

Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia

肝窦阻塞综合征及6-硫鸟嘌呤短期应用治疗儿童急性淋巴细胞白血病

Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning

使用基于基因表达的机器学习预测干细胞基因治疗病毒载体的基因毒性