日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

X-ray diffraction reveals blunt-force loading threshold for nanoscopic structural change in ex vivo neuronal tissues

X射线衍射揭示了离体神经组织纳米级结构变化的钝力加载阈值

Orgel, Joseph; Madhurapantula, Rama S; Eidsmore, Ashley; Wang, Meng; Dutov, Pavel; Modrich, Charles D; Antipova, Olga; McDonald, Jason; Satapathy, Sikhanda

The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease

镉是一种诱变剂和致癌物,也是锌依赖性 MutLα 核酸内切酶的高亲和力抑制剂。

Sherrer, Shanen M; Penland, Elisabeth; Modrich, Paul

Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture)

大肠杆菌和人类错配修复机制(诺贝尔奖演讲)

Modrich, Paul

The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

果蝇拓扑异构酶2的C端20个氨基酸是与含有BRCA1 C端(BRCT)结构域的蛋白质Mus101结合以及DNA分离保真性所必需的

Yu-Tsung Shane Chen ,Jianhong Wu ,Paul Modrich ,Tao-Shih Hsieh

Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system

在特定的体外系统中,人类DNA切除修复与DNA损伤检查点的偶联

Laura A Lindsey-Boltz ,Michael G Kemp, Joyce T Reardon, Vanessa DeRocco, Ravi R Iyer, Paul Modrich, Aziz Sancar

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

BLM-DNA2-RPA-MRN 和 EXO1-BLM-RPA-MRN 构成人类 DNA 断裂修复的两种 DNA 末端切除机制。

Nimonkar, Amitabh V; Genschel, Jochen; Kinoshita, Eri; Polaczek, Piotr; Campbell, Judith L; Wyman, Claire; Modrich, Paul; Kowalczykowski, Stephen C

Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ

人类错配修复蛋白 MutSβ 的纯化、结晶和初步 X 射线衍射分析

Quincy Tseng, Jillian Orans, Michael A Hast, Ravi R Iyer, Anita Changela, Paul L Modrich, Lorena S Beese

Structure of the endonuclease domain of MutL: unlicensed to cut

MutL内切酶结构域的结构:未经许可的切割

Pillon, Monica C; Lorenowicz, Jessica J; Uckelmann, Michael; Klocko, Andrew D; Mitchell, Ryan R; Chung, Yu Seon; Modrich, Paul; Walker, Graham C; Simmons, Lyle A; Friedhoff, Peter; Guarné, Alba

MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbeta

MutLalpha 和增殖细胞核抗原在 MutSbeta 上共享结合位点

Ravi R Iyer, Anna Pluciennik, Jochen Genschel, Miaw-Sheue Tsai, Lorena S Beese, Paul Modrich

Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.

人类错配修复蛋白 MutSalpha 和 MutLalpha 与 ATR-Chk1 通路蛋白的相互作用

Liu Yiyong, Fang Yanan, Shao Hongbing, Lindsey-Boltz Laura, Sancar Aziz, Modrich Paul