日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals

强效的人类CAR激活剂CITCO在人源化组成型雄甾烷受体小鼠中是一种非基因毒性的肝脏肿瘤促进剂，但在野生型动物中则不然。

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-025-03982-9
Henderson, C J; McLaren, A W; MacLeod, A K; Lin, D; Cameron, A R; Chatham, L R; Moggs, J; Inesta-Vaquera, F; Thomson, John P; Meehan, Richard R; Chakravarty, P; Schwarz, M; Wolf, C Roland
信号转导
肿瘤
毒理研究
肿瘤免疫
发表日期：2025
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Unaltered hepatic wound healing response in male rats with ancestral liver injury

具有祖先肝损伤的雄性大鼠肝脏伤口愈合反应未发生改变

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-41998-w
Beil, Johanna; Perner, Juliane; Pfaller, Lena; Gérard, Marie-Apolline; Piaia, Alessandro; Doelemeyer, Arno; Wasserkrug Naor, Adi; Martin, Lori; Piequet, Aline; Dubost, Valérie; Chibout, Salah-Dine; Moggs, Jonathan; Terranova, Rémi
肝损伤
毒理研究
Rat
发表日期：2023
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Correction: The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels

更正：犬种形成的遗传后果——查理王小猎犬中与粘液瘤样二尖瓣疾病相关的有害遗传变异的积累和突变的固定

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1010039
Axelsson, Erik; Ljungvall, Ingrid; Bhoumik, Priyasma; Conn, Laura Bas; Muren, Eva; Ohlsson, Åsa; Olsen, Lisbeth Høier; Engdahl, Karolina; Hagman, Ragnvi; Hanson, Jeanette; Kryvokhyzha, Dmytro; Pettersson, Mats; Grenet, Olivier; Moggs, Jonathan; Rio-Espinola, Alberto Del; Epe, Christian; Taillon, Bruce; Tawari, Nilesh; Mane, Shrinivas; Hawkins, Troy; Hedhammar, Åke; Gruet, Philippe; Häggström, Jens; Lindblad-Toh, Kerstin
发表日期：2022
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The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels

犬种形成的遗传后果——查理王小猎犬中与粘液瘤样二尖瓣疾病相关的有害遗传变异的积累和突变的固定

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1009726
Axelsson, Erik; Ljungvall, Ingrid; Bhoumik, Priyasma; Conn, Laura Bas; Muren, Eva; Ohlsson, Åsa; Olsen, Lisbeth Høier; Engdahl, Karolina; Hagman, Ragnvi; Hanson, Jeanette; Kryvokhyzha, Dmytro; Pettersson, Mats; Grenet, Olivier; Moggs, Jonathan; Del Rio-Espinola, Alberto; Epe, Christian; Taillon, Bruce; Tawari, Nilesh; Mane, Shrinivas; Hawkins, Troy; Hedhammar, Åke; Gruet, Philippe; Häggström, Jens; Lindblad-Toh, Kerstin
发表日期：2021
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A cross-sector call to improve carcinogenicity risk assessment through use of genomic methodologies

跨部门呼吁利用基因组学方法改进致癌性风险评估

期刊:Regulatory Toxicology and Pharmacology
影响因子:3.5
doi:10.1016/j.yrtph.2019.104526
Yauk, Carole L; Harrill, Alison H; Ellinger-Ziegelbauer, Heidrun; van der Laan, Jan Willem; Moggs, Jonathan; Froetschl, Roland; Sistare, Frank; Pettit, Syril
肿瘤
肿瘤免疫
发表日期：2020
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Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion

药物诱导的染色质可及性变化与肝肿瘤促进的敏感性相关

期刊:Life Science Alliance
影响因子:3.3
doi:10.26508/lsa.201900461
Antonio Vitobello, Juliane Perner, Johanna Beil, Jiang Zhu, Alberto Del Río-Espínola, Laurent Morawiec, Magdalena Westphal, Valérie Dubost, Marc Altorfer, Ulrike Naumann, Arne Mueller, Karen Kapur, Mark Borowsky, Colin Henderson, C Roland Wolf, Michael Schwarz, Jonathan Moggs, Rémi Terranova
肿瘤
IL13
发表日期：2019
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Constitutive androstane receptor 1 is constitutively bound to chromatin and 'primed' for transactivation in hepatocytes

组成型雄烷受体 1 与染色质组成性结合，并为肝细胞中的转录激活做好准备

期刊:Molecular Pharmacology
影响因子:3.2
doi:10.1124/mol.118.113555
Michael McMahon, Shaohong Ding, Lourdes Acosta Jimenez, Remi Terranova, Marie-Apolline Gerard, Antonio Vitobello, Jonathan Moggs, Colin J Henderson, C Roland Wolf
细胞生物学
其它细胞
发表日期：2019
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Chromatin dynamics underlying latent responses to xenobiotics

染色质动力学是外源性物质潜在反应的基础

期刊:Toxicology Research
影响因子:2.1
doi:10.1039/c7tx00317j
Moggs, Jonathan; Terranova, Rémi
发表日期：2018
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Defining baseline epigenetic landscapes in the rat liver

定义大鼠肝脏的基线表观遗传景观

期刊:Epigenomics
影响因子:3
doi:10.2217/epi-2017-0029
John P Thomson, Raffaele Ottaviano, Roland Buesen, Jonathan G Moggs, Michael Schwarz, Richard R Meehan
信号转导
Rat
发表日期：2017
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Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer

肝癌中Tet1相关5-羟甲基胞嘧啶的缺失与异常启动子高甲基化同时发生

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-15-1910
Thomson, John P; Ottaviano, Raffaele; Unterberger, Elif B; Lempiäinen, Harri; Muller, Arne; Terranova, Remi; Illingworth, Robert S; Webb, Shaun; Kerr, Alastair R W; Lyall, Marcus J; Drake, Amanda J; Wolf, C Roland; Moggs, Jonathan G; Schwarz, Michael; Meehan, Richard R
肿瘤
肝癌
表观遗传
肿瘤免疫
发表日期：2016
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