IRG1/itaconate/NRF2/GSH axis in tumor-associated macrophages drives therapy resistance and immune evasion in BRCA1-deficient breast cancer.
肿瘤相关巨噬细胞中的 IRG1/衣康酸/NRF2/GSH 轴驱动 BRCA1 缺陷型乳腺癌的治疗耐药性和免疫逃逸。
期刊:
影响因子:
doi:10.1101/2025.10.14.682312
Nan Yabing, O'keefe Sophie, He Xiadi, Luo Qingyu, Wu Xiaowei, Ni Jing, Zou Yutian, Meade Jerryd Marcus, Li Yutong, Ji Renlei, Mohammad Anwaruddin, Kumar Pankaj, Wang Qiwei, Zhao Jean J
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
治疗耐药
乳腺癌
NRF2
BRCA1
细胞生物学
免疫/内分泌