Inhibition of HSP90 by AT13387 delays the emergence of resistance to BRAF inhibitors and overcomes resistance to dual BRAF and MEK inhibition in melanoma models
AT13387 抑制 HSP90 可延缓黑色素瘤模型中对 BRAF 抑制剂耐药性的出现，并克服对 BRAF 和 MEK 双重抑制的耐药性
期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-14-0452
Tomoko Smyth #, Kim H T Paraiso #, Keisha Hearn, Ana M Rodriguez-Lopez, Joanne M Munck, H Eirik Haarberg, Vernon K Sondak, Neil T Thompson, Mohammad Azab, John F Lyons, Keiran S M Smalley, Nicola G Wallis
