Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancer
发现和开发高效且选择性的双重NUAK/MARK抑制剂,作为Hippo通路调节剂用于癌症治疗
期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2026.118798
Smil, David; Liu, Yong; Xin, Tao; Kiyota, Taira; Aman, Ahmed; Grouleff, Julie; Hoffer, Laurent; Joshi, Dhananjay C; Inanlou, Mohammad R; Song, Siyuan; Mao, Daniel Y L; Ogunjimi, Abiodun A; Pau, Victor; Chini, Fiona D; Kurinov, Igor; Zhang, Ying; Nguyen, Anh Thu; Wrana, Jeffrey L; Sicheri, Frank; Attisano, Liliana; Uehling, David; Al-Awar, Rima; Isaac, Methvin B