日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ubiquitin-specific protease 15 interacts directly with the HSV-1 alkaline nuclease and facilitates viral recombination and replication fork stability

泛素特异性蛋白酶15与HSV-1碱性核酸酶直接相互作用,促进病毒重组和复制叉稳定性。

Vue, Yee; Mullon, Patrick J; Leehangin, Alexander; Maldonado-Luevano, Emiliano; Hasselmann, Tyler D; Mehta, Kavi P M; Mohni, Kareem N

The herpes simplex virus alkaline nuclease is required to maintain replication fork progression.

单纯疱疹病毒碱性核酸酶是维持复制叉进展所必需的

Mullon Patrick J, Maldonado-Luevano Emiliano, Mehta Kavi P M, Mohni Kareem N

HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA

HMCES 通过屏蔽单链 DNA 中的无碱基位点来维持基因组完整性

Kareem N Mohni, Sarah R Wessel, Runxiang Zhao, Andrea C Wojciechowski, Jessica W Luzwick, Hillary Layden, Brandt F Eichman, Petria S Thompson, Kavi P M Mehta, David Cortez

Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators

复制叉蛋白质组的功能分析确定 BET 蛋白是 PCNA 调节剂

Sarah R Wessel, Kareem N Mohni, Jessica W Luzwick, Huzefa Dungrawala, David Cortez

An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates

DNA 修复蛋白 Nbs1 的内在无序区域是灵长类动物抵御单纯疱疹病毒 1 的物种特异性屏障

Dianne I Lou, Eui Tae Kim, Nicholas R Meyerson, Neha J Pancholi, Kareem N Mohni, David Enard, Dmitri A Petrov, Sandra K Weller, Matthew D Weitzman, Sara L Sawyer

The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability

复制检查点可防止两种类型的复制叉崩溃,而无需调节复制体稳定性。

Dungrawala, Huzefa; Rose, Kristie L; Bhat, Kamakoti P; Mohni, Kareem N; Glick, Gloria G; Couch, Frank B; Cortez, David

A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments

合成致死筛选可识别出使癌细胞对 ATR 抑制和顺铂联合治疗敏感的 DNA 修复途径

Kareem N Mohni, Petria S Thompson, Jessica W Luzwick, Gloria G Glick, Christopher S Pendleton, Brian D Lehmann, Jennifer A Pietenpol, David Cortez

Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing

原始同源物增强子通过调控RNA加工影响复制应激反应

Kavanaugh, Gina; Zhao, Runxiang; Guo, Yan; Mohni, Kareem N; Glick, Gloria; Lacy, Monica E; Hutson, M Shane; Ascano, Manuel; Cortez, David

ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency

ATR 通路抑制对 ERCC1 缺陷的癌细胞具有综合致死性

Kareem N Mohni, Gina M Kavanaugh, David Cortez

Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response

单纯疱疹病毒1型基因组的结构:对切口和缺口的操控可以消除感染性并改变细胞DNA损伤反应。

Smith, Samantha; Reuven, Nina; Mohni, Kareem N; Schumacher, April J; Weller, Sandra K