Rough endoplasmic reticulum trafficking errors by different classes of mutant dentin sialophosphoprotein (DSPP) cause dominant negative effects in both dentinogenesis imperfecta and dentin dysplasia by entrapping normal DSPP.

不同类别的突变牙本质唾液磷蛋白 (DSPP) 引起的粗面内质网运输错误，会通过捕获正常的 DSPP，对牙本质发育不全和牙本质发育不良产生显性负效应