日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.

APOE3 基因中的 R136S 突变通过抑制 cGAS-STING-IFN 通路赋予机体抵抗 tau 病理的能力

期刊:Immunity
影响因子:26.3
doi:10.1016/j.immuni.2025.05.023
Naguib Sarah, Lopez-Lee Chloe, Torres Eileen Ruth, Lee Se-In, Zhu Jingjie, Zhu Daphne, Ye Pearly, Norman Kendra, Zhao Mingrui, Wong Man Ying, Ambaw Yohannes A, Muñoz-Castañeda Rodrigo, Wang Wei, Patel Tark, Bhagwat Maitreyee, Norinsky Rada, Mok Sue-Ann, Walther Tobias C, Farese Robert V Jr, Luo Wenjie, Sinha Subhash C, Wu Zhuhao, Fan Li, Gong Shiaoching, Gan Li
信号转导
发表日期：2025
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Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo

神经节苷脂调节细胞外囊泡及其错误折叠蛋白货物的分泌。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.ady5212
Monyror, John; Kadam, Vaibhavi; Morales, Luis Carlos; Ordóñez, Diego; Ibanga, Jeremies; Zaidi, Asifa K; McNamara, Emily; Pink, Desmond; Stenlund, Magnus; Reyes, Ken; Maguire, Aislinn D; Huang, Jing; Cortez, Leonardo M; Sim, Valerie L; Mok, Sue-Ann; Posse de Chaves, Elena; Sipione, Simonetta
囊泡
细胞生物学
发表日期：2025
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Inducers and modulators of protein aggregation in Alzheimer's disease - Critical tools for understanding the foundations of aggregate structures

阿尔茨海默病中蛋白质聚集的诱导剂和调节剂——理解聚集结构基础的关键工具

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1016/j.neurot.2024.e00512
Sun, Kerry T; Mok, Sue-Ann
阿尔茨海默症
发表日期：2025
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Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions

体外条件下，天然PLGA纳米颗粒可减弱Tau蛋白的温度依赖性聚集。

期刊:International Journal of Nanomedicine
影响因子:6.5
doi:10.2147/IJN.S494104
Paul, Pallabi Sil; Rathnam, Mallesh; Khalili, Aria; Cortez, Leonardo M; Srinivasan, Mahalashmi; Planel, Emmanuel; Cho, Jae-Young; Wille, Holger; Sim, Valerie L; Mok, Sue-Ann; Kar, Satyabrata
发表日期：2025
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STING-IFN-CH25H lipid axis links innate immune activation to tau pathology

STING-IFN-CH25H脂质轴将先天免疫激活与tau蛋白病理联系起来

期刊:
影响因子:
doi:10.64898/2025.12.16.694702
Chen, Hao; Fan, Li; Wong, Man Ying; Ambaw, Yohannes A; Zhu, Jingjie; Norman, Kendra; Ye, Pearly; Foxe, Nessa; Zhu, Daphne; Wan, Yuansong; Srinivasan, Mahalashmi; Mok, Sue-Ann; McIntire, Laura Beth J; Walther, Tobias C; Farese, Robert V; Gan, Li; Luo, Wenjie
STING
CH25H
免疫/内分泌
发表日期：2025
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Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.

阿尔茨海默病相关风险等位基因在 tau 蛋白病模型中加剧小胶质细胞 cGAS 相关的衰老和神经退行性变

期刊:Neuron
影响因子:15
doi:10.1016/j.neuron.2024.09.006
Carling Gillian K, Fan Li, Foxe Nessa R, Norman Kendra, Wong Man Ying, Zhu Daphne, Corona Carlo, Razzoli Agnese, Yu Fangmin, Yarahmady Allan, Ye Pearly, Chen Hao, Huang Yige, Amin Sadaf, Sereda Rebecca, Lopez-Lee Chloe, Zacharioudakis Emmanouil, Chen Xiaoying, Xu Jielin, Cheng Feixiong, Gavathiotis Evripidis, Cuervo Ana Maria, Holtzman David M, Mok Sue-Ann, Sinha Subhash C, Sidoli Simone, Ratan Rajiv R, Luo Wenjie, Gong Shiaoching, Gan Li
神经科学
细胞生物学
Senescence
细胞衰老
发表日期：2024
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Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure Conformation

Tau蛋白中的疾病相关突变编码聚集体结构构象的改变

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.3c00422
Sun, Kerry T; Patel, Tark; Kang, Sang-Gyun; Yarahmady, Allan; Srinivasan, Mahalashmi; Julien, Olivier; Heras, Jónathan; Mok, Sue-Ann
发表日期：2023
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DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity

DAP12 缺乏会改变小胶质细胞-少突胶质细胞之间的通讯，并增强对 tau 蛋白毒性的抵抗力。

期刊:
影响因子:
doi:10.1101/2023.10.26.563970
Chen, Hao; Fan, Li; Guo, Qi; Wong, Man Ying; Yu, Fangmin; Foxe, Nessa; Wang, Winston; Nessim, Aviram; Carling, Gillian; Liu, Bangyan; Lopez-Lee, Chloe; Huang, Yige; Amin, Sadaf; Patel, Tark; Mok, Sue-Ann; Song, Won-Min; Zhang, Bin; Ma, Qin; Fu, Hongjun; Gan, Li; Luo, Wenjie
胶质细胞
细胞生物学
毒理研究
发表日期：2023
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Deciphering Network Crosstalk: The Current Status and Potential of miRNA Regulatory Networks on the HSP40 Molecular Chaperone Network

解读网络串扰：miRNA调控网络在HSP40分子伴侣网络上的现状与潜力

期刊:Frontiers in Genetics
影响因子:2.8
doi:10.3389/fgene.2021.689922
Budrass, Lion; Fahlman, Richard P; Mok, Sue-Ann
信号转导
miRNA
SP4
发表日期：2021
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Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects

tau蛋白病和创伤性脑损伤中的朊病毒样传播机制：挑战与展望

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom10111487
Alyenbaawi, Hadeel; Allison, W Ted; Mok, Sue-Ann
微生物学
神经科学
发表日期：2020
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