日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-throughput biochemical phenotyping of SHP2 variants reveals the molecular basis of diseases and allosteric drug inhibition

SHP2 变体的高通量生化表型分析揭示了疾病的分子基础和变构药物抑制作用

Lee, Albert A; Mokhtari, Daniel A; Egan, Emily D; Blacklow, Stephen C; Herschlag, Daniel; Fordyce, Polly M

Large field of view fluorescence imaging of microfluidic devices with a tandem-lens macroscope(†)

利用串联透镜宏观显微镜对微流控器件进行大视野荧光成像(†)

Mokhtari, Daniel A; Lashkaripour, Ali; Fordyce, Polly M

Decoupling of catalysis and transition state analog binding from mutations throughout a phosphatase revealed by high-throughput enzymology

高通量酶学揭示磷酸酶中催化作用和过渡态类似物结合的解耦与突变的关系

Markin, Craig J; Mokhtari, Daniel A; Du, Siyuan; Doukov, Tzanko; Sunden, Fanny; Cook, Jordan A; Fordyce, Polly M; Herschlag, Daniel

A microwell platform for high-throughput longitudinal phenotyping and selective retrieval of organoids.

用于高通量纵向表型分析和选择性回收类器官的微孔平台

Sockell Alexandra, Wong Wing, Longwell Scott, Vu Thy, Karlsson Kasper, Mokhtari Daniel, Schaepe Julia, Lo Yuan-Hung, Cornelius Vincent, Kuo Calvin, Van Valen David, Curtis Christina, Fordyce Polly M

Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277†K) and cryo-cooled protein crystals.

评估 X 射线损伤对室温 (277 K) 和低温冷却蛋白质晶体构象异质性的影响

Yabukarski Filip, Doukov Tzanko, Mokhtari Daniel A, Du Siyuan, Herschlag Daniel

Parallel molecular mechanisms for enzyme temperature adaptation

酶温度适应的平行分子机制

Pinney, Margaux M; Mokhtari, Daniel A; Akiva, Eyal; Yabukarski, Filip; Sanchez, David M; Liang, Ruibin; Doukov, Tzanko; Martinez, Todd J; Babbitt, Patricia C; Herschlag, Daniel