Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization
体内控制 Pax6 的过度表达会对 Pax6 基因座进行负向自我调节,导致晚期皮质祖细胞增殖的细胞自主缺陷,而对皮质区域化影响不大
期刊:Development
影响因子:3.7
doi:10.1242/dev.02764
Martine Manuel, Petrina A Georgala, Catherine B Carr, Simon Chanas, Dirk A Kleinjan, Ben Martynoga, John O Mason, Michael Molinek, Jeni Pinson, Thomas Pratt, Jane C Quinn, T Ian Simpson, David A Tyas, Veronica van Heyningen, John D West, David J Price