日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors

针对含GluN2C/2D亚型的NMDA受体的亚型选择性竞争性拮抗作用的结构基础

Wang, Jue Xiang; Irvine, Mark W; Burnell, Erica S; Sapkota, Kiran; Thatcher, Robert J; Li, Minjun; Simorowski, Noriko; Volianskis, Arturas; Collingridge, Graham L; Monaghan, Daniel T; Jane, David E; Furukawa, Hiro

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback

含有GluN2C和GluN2D亚基的NMDA受体在调节神经元振荡中发挥相反的作用;这可能是双向反馈的潜在机制

Mao, Zhihao; He, Shengxi; Mesnard, Christopher; Synowicki, Paul; Zhang, Yuning; Chung, Lucy; Wiesman, Alex I; Wilson, Tony W; Monaghan, Daniel T

Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid

基于2-萘甲酸的N-甲基-D-天冬氨酸受体正负变构调节剂的结构要求研究

Irvine, Mark W; Fang, Guangyu; Sapkota, Kiran; Burnell, Erica S; Volianskis, Arturas; Costa, Blaise M; Culley, Georgia; Collingridge, Graham L; Monaghan, Daniel T; Jane, David E

The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators

NMDA受体胞内C端结构域与变构调节剂相互作用

Sapkota, Kiran; Dore, Kim; Tang, Kang; Irvine, Mark; Fang, Guangyu; Burnell, Erica S; Malinow, Roberto; Jane, David E; Monaghan, Daniel T

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons

在端脑中,GluN2C NMDA受体亚基mRNA主要在神经胶质细胞中表达,而GluN2D mRNA主要在中间神经元中表达。

Alsaad, Hassan A; DeKorver, Nicholas W; Mao, Zhihao; Dravid, Shashank M; Arikkath, Jyothi; Monaghan, Daniel T

The NMDA receptor as a target for cognitive enhancement.

NMDA受体作为认知增强的靶点

Collingridge Graham L, Volianskis Arturas, Bannister Neil, France Grace, Hanna Lydia, Mercier Marion, Tidball Patrick, Fang Guangyu, Irvine Mark W, Costa Blaise M, Monaghan Daniel T, Bortolotto Zuner A, Molnár Elek, Lodge David, Jane David E

Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptors

哌嗪-2,3-二羧酸衍生物作为NMDA和含GluK1的红藻氨酸受体的双重拮抗剂

Irvine, Mark W; Costa, Blaise M; Dlaboga, Daniel; Culley, Georgia R; Hulse, Richard; Scholefield, Caroline L; Atlason, Palmi; Fang, Guangyu; Eaves, Richard; Morley, Richard; Mayo-Martin, Maria B; Amici, Mascia; Bortolotto, Zuner A; Donaldson, Lucy; Collingridge, Graham L; Molnár, Elek; Monaghan, Daniel T; Jane, David E

Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid

基于2-萘甲酸的变构NMDA受体抑制剂的构效关系

Costa, Blaise Mathias; Irvine, Mark W; Fang, Guangyu; Eaves, Richard J; Mayo-Martin, Maria Belen; Laube, Bodo; Jane, David E; Monaghan, Daniel T

Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors

香豆素-3-羧酸衍生物作为重组和天然N-甲基-D-天冬氨酸受体的增强剂和抑制剂

Irvine, Mark W; Costa, Blaise M; Volianskis, Arturas; Fang, Guangyu; Ceolin, Laura; Collingridge, Graham L; Monaghan, Daniel T; Jane, David E

Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators

NMDA受体活性的药理学调节以及负变构调节剂和正变构调节剂的出现

Monaghan, Daniel T; Irvine, Mark W; Costa, Blaise Mathias; Fang, Guangyu; Jane, David E