日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Defining Functional Correction Thresholds in Primary Ciliary Dyskinesia for Effective Gene Therapies

确定原发性纤毛运动障碍功能矫正阈值以实现有效基因治疗

Fitzpatrick, Beck E; Wineinger, Brett J; Babcock, Jason E; Quiroz, Erik J; Liu, Emily C; Gautam, Lalit K; Pezzulo, Alejandro A; Moninger, Thomas O; Meyerholz, David K; Hornick, Douglas B; Ryan, Amy L

Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage

线粒体解偶联蛋白保护人呼吸道上皮纤毛细胞免受氧化损伤

Jain, Akansha; Kim, Bo Ram; Yu, Wenjie; Moninger, Thomas O; Karp, Philip H; Wagner, Brett A; Welsh, Michael J

Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth.

谷胱甘肽过氧化物酶 4 过度表达可诱导异常亚扩散并损害胶质母细胞瘤细胞的生长

Teferi Nahom, Ekanayake Akalanka, Owusu Stephenson B, Moninger Thomas O, Sarkaria Jann N, Tivanski Alexei V, Petronek Michael S

Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia

DNAI1突变和原发性纤毛运动障碍猪的发育和初步表征

Abou Alaiwa, Mahmoud A; Hilkin, Brie M; Price, Margaret P; Gansemer, Nicholas D; Rector, Michael R; Stroik, Mal R; Powers, Linda S; Whitworth, Kristin M; Samuel, Melissa S; Jain, Akansha; Ostedgaard, Lynda S; Ernst, Sarah E; Philibert, Winter; Boyken, Linda D; Moninger, Thomas O; Karp, Phillip H; Hornick, Douglas B; Sinn, Patrick L; Fischer, Anthony J; Pezzulo, Alejandro A; McCray, Paul B Jr; Meyerholz, David K; Zabner, Joseph; Prather, Randy S; Welsh, Michael J; Stoltz, David A

The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion.

沙眼衣原体分泌的效应蛋白TmeA劫持N-WASP-ARP2/3肌动蛋白重塑轴,以促进细胞入侵

Faris Robert, McCullough Alix, Andersen Shelby E, Moninger Thomas O, Weber Mary M

Exocytosis of Progeny Infectious Varicella-Zoster Virus Particles via a Mannose-6-Phosphate Receptor Pathway without Xenophagy following Secondary Envelopment.

子代感染性水痘-带状疱疹病毒颗粒通过甘露糖-6-磷酸受体途径胞吐,无需异噬作用,继发于包膜形成

Girsch James H, Jackson Wallen, Carpenter John E, Moninger Thomas O, Jarosinski Keith W, Grose Charles

Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling

人类呼吸道上皮细胞的运动纤毛含有 Hedgehog 信号通路成分,可介导非经典 Hedgehog 信号通路。

Mao, Suifang; Shah, Alok S; Moninger, Thomas O; Ostedgaard, Lynda S; Lu, Lin; Tang, Xiao Xiao; Thornell, Ian M; Reznikov, Leah R; Ernst, Sarah E; Karp, Philip H; Tan, Ping; Keshavjee, Shaf; Abou Alaiwa, Mahmoud H; Welsh, Michael J

Gel-forming mucins form distinct morphologic structures in airways.

凝胶形成性粘蛋白在气道中形成独特的形态结构

Ostedgaard Lynda S, Moninger Thomas O, McMenimen James D, Sawin Nicholas M, Parker Connor P, Thornell Ian M, Powers Linda S, Gansemer Nicholas D, Bouzek Drake C, Cook Daniel P, Meyerholz David K, Abou Alaiwa Mahmoud H, Stoltz David A, Welsh Michael J

Acidic pH increases airway surface liquid viscosity in cystic fibrosis.

囊性纤维化患者的气道表面液体粘度因酸性pH值升高而增加

Tang Xiao Xiao, Ostedgaard Lynda S, Hoegger Mark J, Moninger Thomas O, Karp Philip H, McMenimen James D, Choudhury Biswa, Varki Ajit, Stoltz David A, Welsh Michael J

Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala

质子是一种神经递质,它调节外侧杏仁核的突触可塑性。

Du, Jianyang; Reznikov, Leah R; Price, Margaret P; Zha, Xiang-ming; Lu, Yuan; Moninger, Thomas O; Wemmie, John A; Welsh, Michael J