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DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis

DLL4+中性粒细胞促进Notch1介导的内皮细胞凋亡，从而加剧脓毒症中的急性肺损伤

期刊:Journal of Clinical Investigation

影响因子:13.3

doi:10.1172/JCI194310

Hui Jin ，Saoirse Holland ，Alok Jha ，Gaifeng Ma ，Jingsong Li ，Atsushi Murao ，Monowar Aziz ，Ping Wang

The role of an anti-inflammatory molecule AIM/CD5L in gut ischemia/reperfusion injury of male mice

抗炎分子AIM/CD5L在雄性小鼠肠道缺血/再灌注损伤中的作用

期刊:Molecular Medicine

影响因子:6

doi:10.1186/s10020-025-01385-1.

Russell Hollis ,Gaifeng Ma ,Alok Jha ,Megan Tenet ,Takayuki Kato ,Monowar Aziz # ,Ping Wang #

Radiation-induced eCIRP causes macrophage phagocytic dysfunction via mitochondrial impairment and ferroptosis

辐射诱导的eCIRP通过线粒体损伤和铁死亡导致巨噬细胞吞噬功能障碍。

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1719613.

Mian Zhou ,Gaifeng Ma ,Jingsong Li ,Satoshi Yamaga ,Max Brenner ,Monowar Aziz # ,Ping Wang #

Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis

鉴定一种能够模拟TLR4的DAMP结合位点的多重DAMP清除剂，以改善致命性脓毒症

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1540908

Takuya Murao ,Gaifeng Ma ,Atsushi Murao ,Alok Jha ,Jingsong Li ,Yongchan Lee ,Mian Zhou ,Ping Wang # ,Monowar Aziz #

A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury

一种靶向中性粒细胞介导的B-1a细胞吞噬作用的新型分子可减轻脓毒症引起的急性肺损伤。

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1597887

Yuichi Akama ，Jespar Chen ，Alok Jha ，Yongchan Lee ，Gaifeng Ma ，Jingsong Li ，Atsushi Murao ，Ping Wang # ，Monowar Aziz #

High‑dose X‑ray irradiation induces NETosis via the eCIRP/TREM‑1 axis in mouse neutrophils

高剂量X射线照射通过eCIRP/TREM-1轴诱导小鼠中性粒细胞胞外陷阱形成（NETosis）

期刊:International Journal of Molecular Medicine

影响因子:5.7

doi:10.3892/ijmm.2025.5598

Satoshi Yamaga ，Atsushi Murao ，Monowar Aziz # ，Ping Wang # ，Max Brenner #

CD300ld promotes neutrophil bacterial phagocytosis in sepsis

CD300ld促进脓毒症中性粒细胞对细菌的吞噬作用

期刊:Journal of Leukocyte Biology

影响因子:3.6

doi:10.1093/jleuko/qiaf063

Yuichi Akama ，Atsushi Murao ，Monowar Aziz ，Ping Wang

Neutrophils disrupt B-1a cell homeostasis by targeting Siglec-G to exacerbate sepsis

中性粒细胞通过靶向Siglec-G破坏B-1a细胞稳态，从而加剧脓毒症。

期刊:Cellular & Molecular Immunology

影响因子:21.8

doi:10.1038/s41423-024-01165-7

Chuyi Tan ，Bridgette Reilly ，Gaifeng Ma ，Atsushi Murao ，Alok Jha ，Monowar Aziz # ，Ping Wang #

An anti-eCIRP strategy for necrotizing enterocolitis

针对坏死性小肠结肠炎的抗 eCIRP 策略

期刊:Molecular Medicine

影响因子:6

doi:10.1186/s10020-024-00935-3

Colleen P Nofi, Jose M Prince, Mariana R Brewer, Monowar Aziz #, Ping Wang #

Gut-primed neutrophils activate Kupffer cells to promote hepatic injury in mouse sepsis

肠道激活的中性粒细胞激活库普弗细胞，促进小鼠脓毒症中的肝损伤

DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis

DLL4+中性粒细胞促进Notch1介导的内皮细胞凋亡，从而加剧脓毒症中的急性肺损伤

The role of an anti-inflammatory molecule AIM/CD5L in gut ischemia/reperfusion injury of male mice

抗炎分子AIM/CD5L在雄性小鼠肠道缺血/再灌注损伤中的作用

Radiation-induced eCIRP causes macrophage phagocytic dysfunction via mitochondrial impairment and ferroptosis

辐射诱导的eCIRP通过线粒体损伤和铁死亡导致巨噬细胞吞噬功能障碍。

Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis

鉴定一种能够模拟TLR4的DAMP结合位点的多重DAMP清除剂，以改善致命性脓毒症

A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury

一种靶向中性粒细胞介导的B-1a细胞吞噬作用的新型分子可减轻脓毒症引起的急性肺损伤。

High‑dose X‑ray irradiation induces NETosis via the eCIRP/TREM‑1 axis in mouse neutrophils

高剂量X射线照射通过eCIRP/TREM-1轴诱导小鼠中性粒细胞胞外陷阱形成（NETosis）

CD300ld promotes neutrophil bacterial phagocytosis in sepsis

CD300ld促进脓毒症中性粒细胞对细菌的吞噬作用

Neutrophils disrupt B-1a cell homeostasis by targeting Siglec-G to exacerbate sepsis

中性粒细胞通过靶向Siglec-G破坏B-1a细胞稳态，从而加剧脓毒症。

An anti-eCIRP strategy for necrotizing enterocolitis

针对坏死性小肠结肠炎的抗 eCIRP 策略