日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.

RAR 抑制剂通过非特异性调节 PPAR 或 RXR 转录激活,在体外 A2E 刺激的 RPE 细胞中表现出光保护和抗炎作用

Fontaine Valérie, Boumedine Thinhinane, Monteiro Elodie, Fournié Mylène, Gersende Gendre, Sahel José-Alain, Picaud Serge, Veillet Stanislas, Lafont René, Latil Mathilde, Dilda Pierre J, Camelo Serge

Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD).

BIO203 是一种新型诺比辛酰胺缀合物,正在开发用于治疗年龄相关性黄斑变性 (AMD),其具有抗炎作用、光保护和神经保护特性

Fontaine Valérie, Balducci Christine, Dinan Laurence, Monteiro Elodie, Boumedine Thinhinane, Fournié Mylène, Nguyen Vincent, Guibout Louis, Clatot Justine, Latil Mathilde, Veillet Stanislas, Sahel José-Alain, Lafont René, Dilda Pierre J, Camelo Serge

Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo

Norbixin在体外和体内均能保护视网膜色素上皮细胞和感光细胞免受A2E介导的光毒性损伤。

Fontaine, Valérie; Monteiro, Elodie; Brazhnikova, Elena; Lesage, Laëtitia; Balducci, Christine; Guibout, Louis; Feraille, Laurence; Elena, Pierre-Paul; Sahel, José-Alain; Veillet, Stanislas; Lafont, René