日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis for GPR40 allosteric agonism and incretin stimulation

GPR40变构激动和肠促胰岛素刺激的结构基础

Ho, Joseph D; Chau, Betty; Rodgers, Logan; Lu, Frances; Wilbur, Kelly L; Otto, Keith A; Chen, Yanyun; Song, Min; Riley, Jonathan P; Yang, Hsiu-Chiung; Reynolds, Nichole A; Kahl, Steven D; Lewis, Anjana Patel; Groshong, Christopher; Madsen, Russell E; Conners, Kris; Lineswala, Jayana P; Gheyi, Tarun; Saflor, Melbert-Brian Decipulo; Lee, Matthew R; Benach, Jordi; Baker, Kenton A; Montrose-Rafizadeh, Chahrzad; Genin, Michael J; Miller, Anne R; Hamdouchi, Chafiq

A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy

一种新型醛固酮拮抗剂可减轻 5/6 肾切除术后的肾损伤

Fujihara, Clarice K; Kowala, M C; Breyer, M D; Sena, Claudia R; Rodrigues, Mariliza V; Arias, Simone C A; Fanelli, Camilla; Malheiros, Denise M; Jadhav, P K; Montrose-Rafizadeh, Chahrzad; Krieger, Jose E; Zatz, Roberto

Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design

使用基于结构的药物设计鉴定用于治疗骨关节炎疼痛的有效且选择性的视黄酸受体γ(RARγ)拮抗剂

Norman E Hughes, Thomas J Bleisch, Scott A Jones, Timothy I Richardson, Robert A Doti, Yong Wang, Stephanie L Stout, Gregory L Durst, Mark G Chambers, Jennifer L Oskins, Chaohua Lin, Lisa A Adams, Todd J Page, Robert J Barr, Richard W Zink, Harold Osborne, Chahrzad Montrose-Rafizadeh, Bryan H Norman

Development of an HTS-compatible assay for discovery of RORα modulators using AlphaScreen® technology

使用 AlphaScreen® 技术开发与 HTS 兼容的检测方法,以发现 RORα 调节剂

Monica A Istrate, Timothy P Spicer, Yan Wang, Jerrold A Bernard, Leah M Helvering, Wayne P Bocchinfuso, Timothy I Richardson, Richard Zink, Naresh Kumar, Chahrzad Montrose-Rafizadeh, Jeffrey Dodge, Peter Hodder, Patrick R Griffin

Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method

利用单一生化方法预测选择性雌激素受体调节剂的组织特异性

Dai, Susie Y; Chalmers, Michael J; Bruning, John; Bramlett, Kelli S; Osborne, Harold E; Montrose-Rafizadeh, Chahrzad; Barr, Robert J; Wang, Yong; Wang, Minmin; Burris, Thomas P; Dodge, Jeffrey A; Griffin, Patrick R

Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats

胰高血糖素样肽-1可以逆转大鼠与年龄相关的葡萄糖耐量下降

Wang, Y; Perfetti, R; Greig, N H; Holloway, H W; DeOre, K A; Montrose-Rafizadeh, C; Elahi, D; Egan, J M

Severe deficiency of cystic fibrosis transmembrane conductance regulator messenger RNA carrying nonsense mutations R553X and W1316X in respiratory epithelial cells of patients with cystic fibrosis

囊性纤维化患者呼吸道上皮细胞中囊性纤维化跨膜传导调节因子信使RNA严重缺乏,并伴有R553X和W1316X无义突变

Hamosh, A; Trapnell, B C; Zeitlin, P L; Montrose-Rafizadeh, C; Rosenstein, B J; Crystal, R G; Cutting, G R