Moon Ryan相关文献与解析，生知库 | 链接生命科学的每一步

Souza-Neto, Fernando; Le, Preston; Abdrabbo, Mobeen; Alamgir, Ashab; Wang, Haiguang; Ferreira de Araujo, Natalia; Mikkila, Jennifer L; Sanches, Bruno; Parthiban, Preethy; Moon, Ryan; Herman, Adam; Adams, Andrew B; Prins, Kurt W; Guatimosim, Silvia; Schuldt, Nathan; Revelo, Xavier S; van Berlo, Jop H

CXCL10

CXCL1

心力衰竭

心血管

发表日期：2026

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Multimodality Molecular Profiling Nominates Targetable Mechanisms in Progressive RV Dysfunction

多模态分子谱分析揭示进行性右心室功能障碍的可靶向机制

期刊:

影响因子:

doi:10.64898/2026.03.09.710504

Mendelson, Jenna B; Sternbach, Jacob; Kim, Minwoo; Raveendran, Rashmi M; Moon, Ryan A; Hartweck, Lynn M; Tollison, Walt; Carney, John P; Markowski, Todd; Higgins, LeeAnn; Prins, Sally E; Kazmirczak, Felipe; Prins, Kurt W

发表日期：2026

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Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs

铁死亡抑制可对抗肺动脉结扎猪的代谢紊乱并改善心脏功能

期刊:American Journal of Respiratory and Critical Care Medicine

影响因子:19.4

doi:10.1164/rccm.202406-1197RL

Kazmirczak, Felipe; Moon, Ryan; Vogel, Neal T; Tollison, Walt; Lahti, Matt T; Carney, John P; Mendelson, Jenna B; Markowski, Todd; Higgins, LeeAnn; Murray, Kevin; Guerrero, Candace; Prins, Kurt W

GP130 Antagonism Enhances Porcine RV Function

GP130拮抗剂增强猪右心室功能

期刊:Circulation Research

影响因子:16.2

doi:10.1161/CIRCRESAHA.125.326336

Mendelson, Jenna B; Sternbach, Jacob D; Kim, Minwoo; Moon, Ryan A; Hartweck, Lynn M; Clark, Sophia R; Tollison, Walt; Lahti, Matthew T; Carney, John P; Markowski, Todd; Higgins, LeeAnn; Kazmirczak, Felipe; Prins, Kurt W

Porcine

发表日期：2025

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Single-Nucleus RNAseq Defines Cellular and Molecular Landscape of Dysfunctional Right Atrium in Pulmonary Artery Banded Swine.

单核 RNA 测序揭示肺动脉束带猪右心房功能障碍的细胞和分子图谱。

期刊:Circulation Research

影响因子:16.2

doi:10.1161/CIRCRESAHA.125.326892

Mendelson Jenna B, Sternbach Jacob D, Kim Minwoo, Moon Ryan A, Blake Jeffrey C, Raveendran Rashmi M, Hartweck Lynn M, Tollison Walt, Lahiri Matthew, Carney John P, Kazmirczak Felipe, Choudhary Gaurav, Prins Kurt W

细胞生物学

发表日期：2025

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Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.

乳酸杆菌重塑微生物/真菌群落，以对抗肺动脉高压中炎症介导的右心室功能障碍

期刊:Circulation-Heart Failure

影响因子:8.4

doi:10.1161/CIRCHEARTFAILURE.124.012524

Prisco Sasha Z, Blake Madelyn, Kazmirczak Felipe, Moon Ryan, Kremer Benjamin P, Hartweck Lynn M, Kim Minwoo, Vogel Neal, Mendelson Jenna B, Moutsoglou Daphne, Thenappan Thenappan, Prins Kurt W

Proteomic and metabolomic profiling nominates druggable targets and biomarkers for pulmonary arterial hypertension-associated myopathy and exercise intolerance in male monocrotaline rats

蛋白质组学和代谢组学分析为单克罗他林雄性大鼠肺动脉高压相关肌病和运动不耐受症确定了可药物靶点和生物标志物

期刊:Journal of Heart and Lung Transplantation

影响因子:6

doi:10.1016/j.healun.2025.06.034

Abreu, Phablo; Moon, Ryan; Mendelson, Jenna B; Markowski, Todd; Higgins, LeeAnn; Murray, Kevin; Guerrero, Candace; Blake, Jeffrey; Prisco, Sasha Z; Prins, Kurt W

Multi-omic Evaluations Nominate an ER-Mitochondrial Axis and Inflammatory Macrophage as Drivers of Right Atrial Dysfunction

多组学评估表明内质网-线粒体轴和炎症巨噬细胞是右心房功能障碍的驱动因素

期刊:

影响因子:

doi:10.1101/2025.03.22.644722

Mendelson, Jenna B; Sternbach, Jacob D; Blake, Jeffrey C; Kim, Minwoo; Moon, Ryan A; Raveendran, Rashmi M; Hartweck, Lynn M; Tollison, Walt; Lahiri, Matthew; Carney, John P; Markowski, Todd; Higgins, LeeAnn; Lewandowski, Cutler T; Kazmirczak, Felipe; Choudhary, Gaurav; Prins, Kurt W

Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy

肺部支链氨基酸代谢受损会促进铁死亡，并导致肺动脉高压相关性肝病。

期刊:

影响因子:

doi:10.1101/2025.09.03.672819

Blake, Madelyn J; Hong, Jason; Brownstein, Adam; Rhodes, Christopher J; Blake, Jeffrey C; Moon, Ryan A; Hartweck, Lynn M; Prisco, Sasha Z; Markowski, Todd; Higgins, LeeAnn; Murray, Kevin; Guerrero, Candance; Breuils-Bonnet, Sandra; Provencher, Steeve; Pepke-Zaba, Joanna; Howard, Luke S; Toshner, Mark; Wilkins, Martin R; Bonnet, Sebastien; Prins, Kurt W

Proteomic and Metabolomic Profiling Nominates Druggable Targets and Biomarkers for Pulmonary Arterial Hypertension-Associated Myopathy and Exercise Intolerance

蛋白质组学和代谢组学分析揭示肺动脉高压相关肌病和运动不耐受的药物靶点和生物标志物

期刊:

影响因子:

doi:10.1101/2025.03.27.644723

Abreu, Phablo; Moon, Ryan; Mendelson, Jenna B; Markowski, Todd; Higgins, LeeAnn; Murray, Kevin; Guerrero, Candace; Blake, Jeffrey; Prisco, Sasha Z; Prins, Kurt W

CXCL10 Regulates Pressure Overload-Induced Heart Failure

CXCL10调节压力超负荷诱发的心力衰竭

Multimodality Molecular Profiling Nominates Targetable Mechanisms in Progressive RV Dysfunction

多模态分子谱分析揭示进行性右心室功能障碍的可靶向机制

Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs

铁死亡抑制可对抗肺动脉结扎猪的代谢紊乱并改善心脏功能

GP130 Antagonism Enhances Porcine RV Function

GP130拮抗剂增强猪右心室功能

Single-Nucleus RNAseq Defines Cellular and Molecular Landscape of Dysfunctional Right Atrium in Pulmonary Artery Banded Swine.

单核 RNA 测序揭示肺动脉束带猪右心房功能障碍的细胞和分子图谱。

Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.

乳酸杆菌重塑微生物/真菌群落，以对抗肺动脉高压中炎症介导的右心室功能障碍

Proteomic and metabolomic profiling nominates druggable targets and biomarkers for pulmonary arterial hypertension-associated myopathy and exercise intolerance in male monocrotaline rats

蛋白质组学和代谢组学分析为单克罗他林雄性大鼠肺动脉高压相关肌病和运动不耐受症确定了可药物靶点和生物标志物

Multi-omic Evaluations Nominate an ER-Mitochondrial Axis and Inflammatory Macrophage as Drivers of Right Atrial Dysfunction

多组学评估表明内质网-线粒体轴和炎症巨噬细胞是右心房功能障碍的驱动因素

Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy

肺部支链氨基酸代谢受损会促进铁死亡，并导致肺动脉高压相关性肝病。

Proteomic and Metabolomic Profiling Nominates Druggable Targets and Biomarkers for Pulmonary Arterial Hypertension-Associated Myopathy and Exercise Intolerance

蛋白质组学和代谢组学分析揭示肺动脉高压相关肌病和运动不耐受的药物靶点和生物标志物