Deep mutational scanning reveals EGFR mutations conferring resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945.
深度突变扫描揭示了 EGFR 突变，这些突变赋予了对第四代 EGFR 酪氨酸激酶抑制剂 BLU-945 的耐药性
期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-025-01086-2
Wang Yueyang, Hao Yuan, Ranieri Michela, Abramyan Tigran M, Tsidilkovski Lev, Hollenberg Michelle, Lopez Alfonso, Moore Xavier T R, Sherman Fiona, Deng Jiehui, Saribekyan Hayk, Papoian Garegin, Wong Kwok-Kin, Shum Elaine, Poirier John T
