Ageing promotes microglial accumulation of slow-degrading synaptic proteins.
衰老会促进小胶质细胞中缓慢降解的突触蛋白的积累。
期刊:Nature
影响因子:48.5
doi:10.1038/s41586-025-09987-9
Guldner Ian H, Wagner Viktoria P, Moran-Losada Patricia, Shi Sophia M, Golub Sophia W, Hevler Johannes F, Chen Kelly, Meese Barbara T, Ghoochani Ali, Pulido Ernst, Oh Hamilton Se-Hwee, Le Guen Yann, Lu Nannan, Wong Pui Shuen, To Ning-Sum, Garceau Dylan, Guo Zimin, Luo Jian, Bertozzi Carolyn R, Lundberg Emma, Abu-Remaileh Monther, Sasner Michael, Keller Andreas, Yang Andrew C, Cheung Tom H, Wyss-Coray Tony