Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice
用强效的TRPC4和TRPC5抑制剂HC-070进行治疗,可使小鼠产生抗焦虑和抗抑郁作用。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0191225
Just, Stefan; Chenard, Bertrand L; Ceci, Angelo; Strassmaier, Timothy; Chong, Jayhong A; Blair, Nathaniel T; Gallaschun, Randall J; Del Camino, Donato; Cantin, Susan; D'Amours, Marc; Eickmeier, Christian; Fanger, Christopher M; Hecker, Carsten; Hessler, David P; Hengerer, Bastian; Kroker, Katja S; Malekiani, Sam; Mihalek, Robert; McLaughlin, Joseph; Rast, Georg; Witek, JoAnn; Sauer, Achim; Pryce, Christopher R; Moran, Magdalene M