日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A bactericidal tuberculosis drug regimen driven by inhibition of the terminal oxidases by pretomanid.

普瑞托马尼通过抑制末端氧化酶发挥杀菌结核病药物治疗作用。

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.1038/s44321-026-00378-9
Rahman Nurlilah Ab, Singh Samsher, Wiggins Thomas, Santos May Delos, Moraski Garrett C, Miller Marvin J, Berney Michael, Pethe Kevin
发表日期：2026
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A Series of Pyrazolo-Quinazoline Amines Inhibits the Cytochrome bd Oxidase in Mycobacterium tuberculosis

一系列吡唑并喹唑啉胺类化合物抑制结核分枝杆菌中的细胞色素bd氧化酶

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01616
Singh, Samsher; Ng, Pearly Shuyi; Lakshmanan, Umayal; Mathiyazakan, Vikneswaran; Wiggins, Thomas; Lee, Bei Shi; Ang, Shi Hua; Lin Sim, Sandra Wei; Santos, May Delos; Moraski, Garrett; Miller, Marvin; Berney, Michael; Grüber, Gerhard; Pethe, Kevin
细胞生物学
发表日期：2026
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QcrB inhibitor Q203 (Telacebec) can synergize with clofazimine and clarithromycin to control a Mycobacterium avium infection

QcrB抑制剂Q203（Telacebec）可与氯法齐明和克拉霉素协同作用，控制鸟分枝杆菌感染。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0344608
Cheng, Yong; Mulvey, Katie; Moraski, Garrett C; Tan, Xuejuan; Mizutare, Toru; Miyagawa, Satoshi; Frey, Carrie; Miller, Marvin J; Schorey, Jeffrey S
炎症/感染
发表日期：2026
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Expanding the Landscape of Dual Action Antifolate Antibacterials through 2,4-Diamino-1,6-dihydro-1,3,5-triazines

通过 2,4-二氨基-1,6-二氢-1,3,5-三嗪类化合物拓展双效抗叶酸抗菌药物的领域

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.4c00768
Georgiades, John D; Berkovich, Daniel A; McKee, Samuel R; Smith, Angela R; Sankaran, Banumathi; Flentie, Kelly N; Castañeda, Carlos H; Grohmann, Daniel G; Rohatgi, Ram; Lasky, Carrie; Mason, Twila A; Champine, James E; Miller, Patricia A; Möllmann, Ute; Moraski, Garrett C; Franzblau, Scott G; Miller, Marvin J; Stallings, Christina L; Jez, Joseph M; Hathaway, Bruce A; Wencewicz, Timothy A
发表日期：2025
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A bioluminescence-based chemical screen identifies a bactericidal naphthalene scaffold targeting MmpL3 in Mycobacterium abscessus

基于生物发光的化学筛选鉴定出一种靶向脓肿分枝杆菌中 MmpL3 的杀菌萘骨架

期刊:
影响因子:
doi:10.1101/2025.10.26.684512
Singh, Samsher; Sorayah, Ria; Chen, Yushu; Mulholland, Claire V; Daher, Wassim; Pee, Carmen J E; Casandra, Tan Ai Zhu; Wee, Denise; Oehlers, Stefan H; Kline, Kimberly A; Chng, Shu Sin; Berney, Michael; Kremer, Laurent; Moraski, Garrett; Pethe, Kevin
发表日期：2025
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GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876

GaMF1.39 的抗生素功效及其与氯法齐明、Telacebec、ND-011992 或 TBAJ-876 联合使用时增强的抗结核活性

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.02282-23
Ragunathan, Priya; Shuyi Ng, Pearly; Singh, Samsher; Poh, Wee Han; Litty, Dennis; Kalia, Nitin Pal; Larsson, Simon; Harikishore, Amaravadhi; Rice, Scott A; Ingham, Philip W; Müller, Volker; Moraski, Garrett; Miller, Marvin J; Dick, Thomas; Pethe, Kevin; Grüber, Gerhard
发表日期：2023
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Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties

合成及研究具有强效抗结核活性和改善的代谢特性的氘代咪唑并[1,2-a]吡啶-3-甲酰胺类化合物

期刊:Bioorganic Chemistry
影响因子:4.7
doi:10.1016/j.bioorg.2022.106074
Liu, Rui; Marshall, Kate; Ma, Rui; Lien Thi Pham, Kim; Shetye, Gauri; Liu, Zhihao; Cho, Sanghyun; Jeong, Hyunyoung; Franzblau, Scott G; Moraski, Garrett C; Miller, Marvin J
代谢
发表日期：2022
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The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus

QcrB抑制剂TB47和Telacebec不会增强氯法齐明对脓肿分枝杆菌的活性。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00964-21
Sorayah, Ria; Moraski, Garret C; Barkan, Daniel; Pethe, Kevin
发表日期：2021
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Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds

氢化物诱导的迈森海默复合物的形成反映了硝基芳香族抗结核化合物的活性。

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d0md00390e
Liu, Rui; Markley, Lowell; Miller, Patricia A; Franzblau, Scott; Shetye, Gauri; Ma, Rui; Savková, Karin; Mikušová, Katarína; Lee, Bei Shi; Pethe, Kevin; Moraski, Garrett C; Miller, Marvin J
发表日期：2021
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Structure guided generation of thieno[3,2-d]pyrimidin-4-amine Mycobacterium tuberculosis bd oxidase inhibitors

结构导向合成噻吩并[3,2-d]嘧啶-4-胺结核分枝杆菌bd氧化酶抑制剂

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d0md00398k
Hopfner, Sarah M; Lee, Bei Shi; Kalia, Nitin P; Miller, Marvin J; Pethe, Kevin; Moraski, Garrett C
发表日期：2021
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