日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A bactericidal tuberculosis drug regimen driven by inhibition of the terminal oxidases by pretomanid.

普瑞托马尼通过抑制末端氧化酶发挥杀菌结核病药物治疗作用。

Rahman Nurlilah Ab, Singh Samsher, Wiggins Thomas, Santos May Delos, Moraski Garrett C, Miller Marvin J, Berney Michael, Pethe Kevin

QcrB inhibitor Q203 (Telacebec) can synergize with clofazimine and clarithromycin to control a Mycobacterium avium infection

QcrB抑制剂Q203(Telacebec)可与氯法齐明和克拉霉素协同作用,控制鸟分枝杆菌感染。

Cheng, Yong; Mulvey, Katie; Moraski, Garrett C; Tan, Xuejuan; Mizutare, Toru; Miyagawa, Satoshi; Frey, Carrie; Miller, Marvin J; Schorey, Jeffrey S

Expanding the Landscape of Dual Action Antifolate Antibacterials through 2,4-Diamino-1,6-dihydro-1,3,5-triazines

通过 2,4-二氨基-1,6-二氢-1,3,5-三嗪类化合物拓展双效抗叶酸抗菌药物的领域

Georgiades, John D; Berkovich, Daniel A; McKee, Samuel R; Smith, Angela R; Sankaran, Banumathi; Flentie, Kelly N; Castañeda, Carlos H; Grohmann, Daniel G; Rohatgi, Ram; Lasky, Carrie; Mason, Twila A; Champine, James E; Miller, Patricia A; Möllmann, Ute; Moraski, Garrett C; Franzblau, Scott G; Miller, Marvin J; Stallings, Christina L; Jez, Joseph M; Hathaway, Bruce A; Wencewicz, Timothy A

Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties

合成及研究具有强效抗结核活性和改善的代谢特性的氘代咪唑并[1,2-a]吡啶-3-甲酰胺类化合物

Liu, Rui; Marshall, Kate; Ma, Rui; Lien Thi Pham, Kim; Shetye, Gauri; Liu, Zhihao; Cho, Sanghyun; Jeong, Hyunyoung; Franzblau, Scott G; Moraski, Garrett C; Miller, Marvin J

Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds

氢化物诱导的迈森海默复合物的形成反映了硝基芳香族抗结核化合物的活性。

Liu, Rui; Markley, Lowell; Miller, Patricia A; Franzblau, Scott; Shetye, Gauri; Ma, Rui; Savková, Karin; Mikušová, Katarína; Lee, Bei Shi; Pethe, Kevin; Moraski, Garrett C; Miller, Marvin J

Structure guided generation of thieno[3,2-d]pyrimidin-4-amine Mycobacterium tuberculosis bd oxidase inhibitors

结构导向合成噻吩并[3,2-d]嘧啶-4-胺结核分枝杆菌bd氧化酶抑制剂

Hopfner, Sarah M; Lee, Bei Shi; Kalia, Nitin P; Miller, Marvin J; Pethe, Kevin; Moraski, Garrett C

Syntheses and Structure-Activity Relationships of N-Phenethyl-Quinazolin-4-yl-Amines as Potent Inhibitors of Cytochrome bd Oxidase in Mycobacterium tuberculosis

N-苯乙基-喹唑啉-4-基胺类化合物作为结核分枝杆菌细胞色素bd氧化酶强效抑制剂的合成及构效关系研究

Hopfner, Sarah M; Lee, Bei Shi; Kalia, Nitin P; Miller, Marvin J; Pethe, Kevin; Moraski, Garrett C

Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc(1):aa(3) in Mycobacterium tuberculosis

碳代谢调节靶向结核分枝杆菌细胞色素bc(1):aa(3)的药物的疗效

Kalia, Nitin P; Shi Lee, Bei; Ab Rahman, Nurlilah B; Moraski, Garrett C; Miller, Marvin J; Pethe, Kevin

PvdF of pyoverdin biosynthesis is a structurally unique N(10)-formyltetrahydrofolate-dependent formyltransferase

绿脓菌素生物合成中的 PvdF 是一种结构独特的 N(10)-甲酰四氢叶酸依赖性甲酰转移酶

Kenjić, Nikola; Hoag, Matthew R; Moraski, Garrett C; Caperelli, Carol A; Moran, Graham R; Lamb, Audrey L

Targeting the Mycobacterium ulcerans cytochrome bc(1):aa(3) for the treatment of Buruli ulcer.

以溃疡分枝杆菌细胞色素bc(1):aa(3)为靶点治疗布鲁里溃疡

Scherr Nicole, Bieri Raphael, Thomas Sangeeta S, Chauffour Aurélie, Kalia Nitin Pal, Schneide Paul, Ruf Marie-Thérèse, Lamelas Araceli, Manimekalai Malathy S S, Grüber Gerhard, Ishii Norihisa, Suzuki Koichi, Tanner Marcel, Moraski Garrett C, Miller Marvin J, Witschel Matthias, Jarlier Vincent, Pluschke Gerd, Pethe Kevin