Crystal structures reveal phosphorylation-dependent disruption of the heat shock protein 70-CHIP interface: A compensatory G132N variant restores binding affinity
晶体结构揭示了磷酸化依赖性的热休克蛋白70-CHIP界面破坏:补偿性G132N变体恢复了结合亲和力
期刊:Cell Stress & Chaperones
影响因子:3.2
doi:10.1016/j.cstres.2026.100166
Stewart, Mariah; Paththamperuma, Chathura; McCann, Colleen; Cottingim, Kelsey; Zhang, Huaqun; DelVecchio, Rian; Peng, Ivy; Fennimore, Erica; Nix, Jay C; Saeed, Morcos N; George, Kathleen; Makaroff, Katherine; Colie, Meagan; Paulakonis, Ethan; Almeida, Michael F; Afolayan, Adeleye J; Brown, Nicholas G; Page, Richard C; Schisler, Jonathan C