Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach
利用共价片段筛选方法鉴定具有细胞活性的基孔肯雅病毒nsP2蛋白酶抑制剂
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2409166121
Merten, Eric M; Sears, John D; Leisner, Tina M; Hardy, P Brian; Ghoshal, Anirban; Hossain, Mohammad Anwar; Asressu, Kesatebrhan Haile; Brown, Peter J; Tse, Edwin G; Stashko, Michael A; Li, Kelin; Norris-Drouin, Jacqueline L; Herring, Laura E; Mordant, Angie L; Webb, Thomas S; Mills, Christine A; Barker, Natalie K; Streblow, Zachary J; Perveen, Sumera; Arrowsmith, Cheryl H; Couñago, Rafael Miguez; Arnold, Jamie J; Cameron, Craig E; Streblow, Daniel N; Moorman, Nathaniel J; Heise, Mark T; Willson, Timothy M; Popov, Konstantin I; Pearce, Kenneth H