日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma.

细胞周期蛋白 D1 过表达可诱导套细胞淋巴瘤的复制压力和微同源介导的末端连接依赖性

Abeykoon Jithma P, Asada Shuhei, Zhu Guangli, Hirohashi Yuna, Moreau Lisa, Iyer Divya, Mukkavalli Sirisha, Parmar Kalindi, Zambrano Gabriella, Jiang Lige, Yi Dongni, Manske Michelle, Gwin Kimberly, King Rebecca L, Cerhan James R, Wu Xiaosheng, Lou Zhenkun, Shapiro Geoffrey I, Witzig Thomas, D'Andrea Alan

A porcine model of Fanconi anemia

范可尼贫血症的猪模型

Hergert, Brandon; Whitworth, Kristin M; Goldman, Devorah C; Moreau, Lisa; McQueen, Kelsey; Parmar, Kalindi; D'Andrea, Alan; Samuel, Melissa S; Wells, Kevin D; Prather, Randall S; Dorell, Craig; Grompe, Markus; Fleming, William H

Metformin for treatment of cytopenias in children and young adults with Fanconi anemia

二甲双胍用于治疗范可尼贫血症患儿和青少年的血细胞减少症

Pollard, Jessica A; Furutani, Elissa; Liu, Shanshan; Esrick, Erica; Cohen, Laurie E; Bledsoe, Jacob; Liu, Chih-Wei; Lu, Kun; de Haro, Maria Jose Ramirez; Surrallés, Jordi; Malsch, Maggie; Kuniholm, Ashley; Galvin, Ashley; Armant, Myriam; Kim, Annette S; Ballotti, Kaitlyn; Moreau, Lisa; Zhou, Yu; Babushok, Daria; Boulad, Farid; Carroll, Clint; Hartung, Helge; Hont, Amy; Nakano, Taizo; Olson, Tim; Sze, Sei-Gyung; Thompson, Alexis A; Wlodarski, Marcin W; Gu, Xuesong; Libermann, Towia A; D'Andrea, Alan; Grompe, Markus; Weller, Edie; Shimamura, Akiko

TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia

TGF-β抑制剂可挽救范可尼贫血症的造血干细胞缺陷和骨髓衰竭

Zhang, Haojian; Kozono, David E; O'Connor, Kevin W; Vidal-Cardenas, Sofia; Rousseau, Alix; Hamilton, Abigail; Moreau, Lisa; Gaudiano, Emily F; Greenberger, Joel; Bagby, Grover; Soulier, Jean; Grompe, Markus; Parmar, Kalindi; D'Andrea, Alan D

Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype

BRCA1基因的双等位基因突变导致一种新的范可尼贫血亚型

Sawyer, Sarah L; Tian, Lei; Kähkönen, Marketta; Schwartzentruber, Jeremy; Kircher, Martin; Majewski, Jacek; Dyment, David A; Innes, A Micheil; Boycott, Kym M; Moreau, Lisa A; Moilanen, Jukka S; Greenberg, Roger A

Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice

Uaf1基因失活会导致小鼠同源重组缺陷和早期胚胎致死。

Park, Eunmi; Kim, Jung Min; Primack, Benjamin; Weinstock, David M; Moreau, Lisa A; Parmar, Kalindi; D'Andrea, Alan D

Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia

急性髓系白血病中MET受体酪氨酸激酶的自分泌激活

Kentsis, Alex; Reed, Casie; Rice, Kim L; Sanda, Takaomi; Rodig, Scott J; Tholouli, Eleni; Christie, Amanda; Valk, Peter J M; Delwel, Ruud; Ngo, Vu; Kutok, Jeffery L; Dahlberg, Suzanne E; Moreau, Lisa A; Byers, Richard J; Christensen, James G; Vande Woude, George; Licht, Jonathan D; Kung, Andrew L; Staudt, Louis M; Look, A Thomas

Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents

抑制Nedd8系统会使细胞对DNA链间交联剂更加敏感

Kee, Younghoon; Huang, Min; Chang, Sophia; Moreau, Lisa A; Park, Eunmi; Smith, Peter G; D'Andrea, Alan D

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

CDK1活性受损会使具有BRCA功能的癌症对PARP抑制剂更加敏感

Johnson, Neil; Li, Yu-Chen; Walton, Zandra E; Cheng, Katherine A; Li, Danan; Rodig, Scott J; Moreau, Lisa A; Unitt, Christine; Bronson, Roderick T; Thomas, Huw D; Newell, David R; D'Andrea, Alan D; Curtin, Nicola J; Wong, Kwok-Kin; Shapiro, Geoffrey I

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

组蛋白 H3 甲基化将 DNA 损伤检测与肿瘤抑制因子 Tip60 的激活联系起来

Sun Yingli, Jiang Xiaofeng, Xu Ye, Ayrapetov Marina K, Moreau Lisa A, Whetstine Johnathan R, Price Brendan D