日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Two-pore channels: going with the flows

双孔通道:顺流而下

Morgan, Anthony J; Martucci, Lora L; Davis, Lianne C; Galione, Antony

NAADP-regulated two-pore channels drive phagocytosis through endo-lysosomal Ca(2+) nanodomains, calcineurin and dynamin.

NAADP 调节的双孔通道通过内溶酶体 Ca(2+) 纳米域、钙调磷酸酶和动力蛋白驱动吞噬作用

Davis Lianne C, Morgan Anthony J, Galione Antony

Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation

端粒酶在人体微循环血流介导扩张机制中的关键作用

Andreas M Beyer, Julie K Freed, Matthew J Durand, Michael Riedel, Karima Ait-Aissa, Paula Green, Joseph C Hockenberry, R Garret Morgan, Anthony J Donato, Refael Peleg, Mario Gasparri, Chris K Rokkas, Janine H Santos, Esther Priel, David D Gutterman

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells

烟酸腺嘌呤二核苷酸磷酸(NAADP)和内溶酶体双孔通道调节小鼠胰岛β细胞的膜兴奋性和刺激-分泌偶联

Arredouani, Abdelilah; Ruas, Margarida; Collins, Stephan C; Parkesh, Raman; Clough, Frederick; Pillinger, Toby; Coltart, George; Rietdorf, Katja; Royle, Andrew; Johnson, Paul; Braun, Matthias; Zhang, Quan; Sones, William; Shimomura, Kenju; Morgan, Anthony J; Lewis, Alexander M; Chuang, Kai-Ting; Tunn, Ruth; Gadea, Joaquin; Teboul, Lydia; Heister, Paula M; Tynan, Patricia W; Bellomo, Elisa A; Rutter, Guy A; Rorsman, Patrik; Churchill, Grant C; Parrington, John; Galione, Antony

Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1

小鼠和人类尼曼-匹克病C1型中自然杀伤细胞的分布和功能改变

Speak, Anneliese O; Te Vruchte, Danielle; Davis, Lianne C; Morgan, Anthony J; Smith, David A; Yanjanin, Nicole M; Simmons, Louise; Hartung, Ralf; Runz, Heiko; Mengel, Eugen; Beck, Michael; Imrie, Jackie; Jacklin, Elizabeth; Wraith, James E; Hendriksz, Christian; Lachmann, Robin; Cognet, Celine; Sidhu, Rohini; Fujiwara, Hideji; Ory, Daniel S; Galione, Antony; Porter, Forbes D; Vivier, Eric; Platt, Frances M

NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing

NAADP激活T细胞细胞溶解颗粒上的双孔通道,从而刺激胞吐作用和杀伤作用。

Davis, Lianne C; Morgan, Anthony J; Chen, Ji-Li; Snead, Charlotte M; Bloor-Young, Duncan; Shenderov, Eugene; Stanton-Humphreys, Megan N; Conway, Stuart J; Churchill, Grant C; Parrington, John; Cerundolo, Vincenzo; Galione, Antony

The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release

管腔内Ca²⁺螯合剂TPEN抑制NAADP诱导的Ca²⁺释放

Morgan, Anthony J; Parrington, John; Galione, Antony

Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites

Ca(2+)信号传导是通过细胞器内合成位点释放第二信使实现的。

Davis, Lianne C; Morgan, Anthony J; Ruas, Margarida; Wong, Julian L; Graeff, Richard M; Poustka, Albert J; Lee, Hon Cheung; Wessel, Gary M; Parrington, John; Galione, Antony