日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation

肿瘤靶向CD40激动剂CEA-CD40通过双重作用机制促进T细胞启动:一方面增加抗原向树突状细胞的递送,另一方面增强其活化。

Eva Sum ,Moritz Rapp ,Harald Dürr ,Alekhya Mazumdar ,Pedro J Romero ,Christine Trumpfheller ,Pablo Umaña

T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours

携带 CXC 趋化因子受体 6 型的 T 细胞可增强胰腺肿瘤的过继细胞治疗

Stefanie Lesch #, Viktoria Blumenberg #, Stefan Stoiber, Adrian Gottschlich, Justyna Ogonek, Bruno L Cadilha, Zahra Dantes, Felicitas Rataj, Klara Dorman, Johannes Lutz, Clara H Karches, Constanze Heise, Mathias Kurzay, Benjamin M Larimer, Simon Grassmann, Moritz Rapp, Alessia Nottebrock, Stephan Kr

Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity

成纤维细胞活化蛋白 α 靶向 CD40 激动剂可消除全身毒性,并能通过高剂量给药诱导有效的抗肿瘤免疫

Eva Sum #, Moritz Rapp #, Philipp Fröbel, Marine Le Clech, Harald Dürr, Anna Maria Giusti, Mario Perro, Dario Speziale, Leo Kunz, Elena Menietti, Peter Brünker, Ulrike Hopfer, Martin Lechmann, Andrzej Sobieniecki, Birte Appelt, Roberto Adelfio, Valeria Nicolini, Anne Freimoser-Grundschober, Whitney

Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells

STAT5在自然杀伤细胞适应性反应中的不同作用

Gabriela M Wiedemann ,Simon Grassmann ,Colleen M Lau ,Moritz Rapp ,Alejandro V Villarino ,Christin Friedrich ,Georg Gasteiger ,John J O'Shea ,Joseph C Sun

CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes

CCL22通过促进调节性T细胞与淋巴结中树突状细胞的通讯来控制免疫

Moritz Rapp, Maximilian W M Wintergerst, Wolfgang G Kunz, Viola K Vetter, Max M L Knott, Dominik Lisowski, Sascha Haubner, Stefan Moder, Raffael Thaler, Stephan Eiber, Bastian Meyer, Natascha Röhrle, Ignazio Piseddu, Simon Grassmann, Patrick Layritz, Benjamin Kühnemuth, Susanne Stutte, Carole Bourqu

Epigenetic control of innate and adaptive immune memory

先天性和适应性免疫记忆的表观遗传控制

Colleen M Lau ,Nicholas M Adams ,Clair D Geary ,Orr-El Weizman ,Moritz Rapp ,Yuri Pritykin ,Christina S Leslie ,Joseph C Sun

Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response

转录因子IRF8调控适应性自然杀伤细胞反应

Nicholas M Adams, Colleen M Lau, Xiying Fan, Moritz Rapp, Clair D Geary, Orr-El Weizman, Carlos Diaz-Salazar, Joseph C Sun

Atg5 Is Essential for the Development and Survival of Innate Lymphocytes

Atg5 对于先天淋巴细胞的发育和存活至关重要

Timothy E O'Sullivan, Clair D Geary, Orr-El Weizman, Theresa L Geiger, Moritz Rapp, Gerald W Dorn 2nd, Michael Overholtzer, Joseph C Sun