日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Elimination of CDX2 restricts intestinal hybrid differentiation signatures in stem cell-derived hepatocyte-like cells

CDX2的缺失会限制干细胞来源的肝细胞样细胞的肠道杂交分化特征。

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04696-6
Nell, Patrick; Thomitzek, Antonia; Feuerborn, David; Scholtz-Illigens, Andreas; Seidel, Sarah M; Derksen, Katharina; Chilinski, Lara Maria; Kattler-Lackes, Kathrin; Blüthgen, Nils; Morkel, Markus; Walter, Jörn; Edlund, Karolina; Rahnenführer, Jörg; Hengstler, Jan G
细胞生物学
发育与干细胞
CDX2
干细胞
发表日期：2025
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GPA33 expression in colorectal cancer can be induced by WNT inhibition and targeted by cellular therapy.

结直肠癌中 GPA33 的表达可通过 WNT 抑制诱导，并可通过细胞疗法进行靶向治疗

期刊:Oncogene
影响因子:7.3
doi:10.1038/s41388-024-03200-3
Börding Teresa, Janik Tobias, Bischoff Philip, Morkel Markus, Sers Christine, Horst David
细胞生物学
肠癌
肿瘤免疫
发表日期：2025
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Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue

对患者匹配的新鲜和福尔马林固定石蜡包埋 (FFPE) 肺癌组织的单细胞 RNA 谱中具有临床相关特征的稳健检测

期刊:Cellular Oncology
影响因子:4.8
doi:10.1007/s13402-024-00922-0
Trinks, Alexandra; Milek, Miha; Beule, Dieter; Kluge, Julie; Florian, Stefan; Sers, Christine; Horst, David; Morkel, Markus; Bischoff, Philip
肺癌
肿瘤
肿瘤免疫
细胞生物学
单细胞
发表日期：2024
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Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression

在早期结直肠癌进展中，恶性转化和基因改变是分离的。

期刊:BMC Biology
影响因子:4.5
doi:10.1186/s12915-020-00844-x
Mamlouk, Soulafa; Simon, Tincy; Tomás, Laura; Wedge, David C; Arnold, Alexander; Menne, Andrea; Horst, David; Capper, David; Morkel, Markus; Posada, David; Sers, Christine; Bläker, Hendrik
肿瘤
肠癌
肿瘤免疫
发表日期：2020
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DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer

对小鼠肠道腺瘤的DNA甲基化组分析发现了一种肿瘤特异性特征，该特征在人类结肠癌中部分保守。

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1003250
Grimm, Christina; Chavez, Lukas; Vilardell, Mireia; Farrall, Alexandra L; Tierling, Sascha; Böhm, Julia W; Grote, Phillip; Lienhard, Matthias; Dietrich, Jörn; Timmermann, Bernd; Walter, Jörn; Schweiger, Michal R; Lehrach, Hans; Herwig, Ralf; Herrmann, Bernhard G; Morkel, Markus
肿瘤
肠癌
表观遗传
肿瘤免疫
DNA甲基化
发表日期：2013
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Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells

鉴定Y盒结合蛋白1为结直肠癌细胞中MEK/ERK通路依赖性基因表达的核心调控因子

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1001231
Jürchott, Karsten; Kuban, Ralf-Jürgen; Krech, Till; Blüthgen, Nils; Stein, Ulrike; Walther, Wolfgang; Friese, Christian; Kiełbasa, Szymon M; Ungethüm, Ute; Lund, Per; Knösel, Thomas; Kemmner, Wolfgang; Morkel, Markus; Fritzmann, Johannes; Schlag, Peter M; Birchmeier, Walter; Krueger, Tammo; Sperling, Silke; Sers, Christine; Royer, Hans-Dieter; Herzel, Hanspeter; Schäfer, Reinhold
肿瘤
肠癌
肿瘤免疫
信号转导
MAPK/ERK
细胞生物学
发表日期：2010
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