日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Design of a Targeted Covalent Probe to Interrogate the DNA Polymerase Activity of Polθ

设计靶向共价探针以检测Polθ的DNA聚合酶活性

Bubenik, Monica; Mader, Pavel; Orlicky, Stephen; Perryman, Alexander L; Hamel, Martine; Godbout, Claude; Falgueyret, Jean-Pierre; Kurinov, Igor; Wong, Cassandra; Gingras, Anne Claude; Mamane, Yael; Zinda, Michael; Morris, Stephen J; Gallant, Michel; Sfeir, Agnel; Black, W Cameron; Durocher, Daniel; Zimmermann, Michal; Sicheri, Frank

Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells

评估短发夹 RNA 在开发含 shRNA 的 CAR-T 细胞中的作用

Ryan Urak, Brenna Gittins, Citradewi Soemardy, Nicole Grepo, Lior Goldberg, Madeleine Maker, Galina Shevchenko, Alicia Davis, Shirley Li, Tristan Scott, Kevin V Morris, Stephen J Forman, Xiuli Wang

Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia

AEG35156 X连锁凋亡蛋白反义寡核苷酸联合伊达比星和阿糖胞苷治疗复发或原发性难治性急性髓系白血病患者的I/II期临床试验

Schimmer, Aaron D; Estey, Elihu H; Borthakur, Gautam; Carter, Bing Z; Schiller, Gary J; Tallman, Martin S; Altman, Jessica K; Karp, Judith E; Kassis, Jeannine; Hedley, David W; Brandwein, Joseph; Xu, Wei; Mak, Duncan H; LaCasse, Eric; Jacob, Christine; Morris, Stephen J; Jolivet, Jacques; Andreeff, Michael

Cytoprotective effects of IAPs revealed by a small molecule antagonist

小分子拮抗剂揭示了IAP的细胞保护作用

Galbán, Stefanie; Hwang, Clara; Rumble, Julie M; Oetjen, Karolyn A; Wright, Casey W; Boudreault, Alain; Durkin, Jon; Gillard, John W; Jaquith, James B; Morris, Stephen J; Duckett, Colin S

Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion.

结直肠癌中缺失的结合蛋白 netrin-1 介导细胞底物粘附,并将 Cdc42、Rac1、Pak1 和 N-WASP 募集到细胞内信号复合物中,从而促进生长锥扩张

Shekarabi Masoud, Moore Simon W, Tritsch Nicolas X, Morris Stephen J, Bouchard Jean-Francois, Kennedy Timothy E