日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KCC2 activation during postnatal development alleviates long-term deficits in CDKL5-deficient mice

出生后发育过程中KCC2的激活可缓解CDKL5缺陷小鼠的长期功能障碍。

Arshad, Muhammad Nauman; Bope, Christopher; Cho, Noell; Dengler, Jacob S; Ng, Shu Fun Josephine; Smalley, Joshua L; Nishi, Toshiya; Zhong, Zhong; Moss, Stephen J; Davies, Paul A

KCC2 Activation Reverses Neurophysiological and Behavioral Deficits in Female Rett Mice

KCC2激活可逆转雌性Rett小鼠的神经生理和行为缺陷

Arshad, Muhammad Nauman; Ng, Shu Fun Josephine; Salar, Seda; Abiraman, Krithika; Nishi, Toshiya; Zhong, Zhong; Smalley, Joshua L; Davies, Paul A; Moss, Stephen J

Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy

p38α介导的磷酸化和PRMT1介导的精氨酸甲基化在驱动TDP-43蛋白病中发挥相反的作用

Aikio, Mari; Odeh, Hana M; Wobst, Heike J; Lee, Bo Lim; Chan, Úna; Mauna, Jocelyn C; Mack, Korrie L; Class, Bradley; Ollerhead, Thomas A; Ford, Alice F; Barbieri, Edward M; Cupo, Ryan R; Drake, Lauren E; Smalley, Joshua L; Lin, Yuan-Ta; Lam, Stephanie; Thomas, Reuben; Castello, Nicholas; Baral, Ashmita; Beyer, Jenna N; Najar, Mohd A; Dunlop, John; Gitler, Aaron D; Javaherian, Ashkan; Kaye, Julia A; Burslem, George M; Brown, Dean G; Donnelly, Christopher J; Finkbeiner, Steven; Moss, Stephen J; Brandon, Nicholas J; Shorter, James

Neuroactive steroids activate membrane progesterone receptors to induce sex specific effects on protein kinase activity.

神经活性类固醇激活膜孕酮受体,从而对蛋白激酶活性产生性别特异性影响

Lemons Abigail H S, Murphy Briana, Dengler Jake S, Salar Seda, Davies Paul A, Smalley Joshua L, Moss Stephen J

KCC2 inhibition and neuronal hyperexcitability promote extrinsic apoptosis dependent upon C1q.

KCC2抑制和神经元过度兴奋促进依赖于C1q的外源性细胞凋亡

Ji Jinglin, Choi Catherine, Bope Christopher E, Dengler Jacob S, Moss Stephen J, Smalley Joshua L

Neuroactive steroids activate membrane progesterone receptors to induce sex specific effects on protein kinase activity

神经活性类固醇激活膜孕酮受体,从而对蛋白激酶活性产生性别特异性影响。

Lemons, Abigail H S; Murphy, Briana; Dengler, Jake S; Salar, Seda; Davies, Paul A; Smalley, Joshua L; Moss, Stephen J

Activation of KCC2 during development alleviates cognitive, behavioral, and neural excitability in adult CDKL5-deficient mice

发育过程中KCC2的激活可减轻成年CDKL5缺陷小鼠的认知、行为和神经兴奋性。

Arshad, Muhammad Nauman; Bope, Christopher; Dengler, Jacob S; Ng, Shu Fun Josephine; Smalley, Joshua; Nishi, Toshiya; Zhong, Zhong; Moss, Stephen J; Davies, Paul A

A revised nomenclature for the lemur family of protein kinases

狐猴蛋白激酶家族命名法的修订

Mórotz, Gábor M; Bradbury, Neil A; Caluseriu, Oana; Hisanaga, Shin-Ichi; Miller, Christopher C J; Swiatecka-Urban, Agnieszka; Lenz, Heinz-Josef; Moss, Stephen J; Giamas, Georgios

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA(A) receptor α2 subunit

人类 ARHGEF9 智力障碍综合征的表型可由一种破坏 collybistin 与 GABA(A) 受体 α2 亚基结合的突变所模拟。

Hines, Dustin J; Contreras, April; Garcia, Betsua; Barker, Jeffrey S; Boren, Austin J; Moufawad El Achkar, Christelle; Moss, Stephen J; Hines, Rochelle M

Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme

舞蹈病相关的PDE10A基因突变会导致该酶的区室化和功能异常。

Tejeda, Gonzalo S; Whiteley, Ellanor L; Deeb, Tarek Z; Bürli, Roland W; Moss, Stephen J; Sheridan, Eamonn; Brandon, Nicholas J; Baillie, George S