日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Beta cell-targeted PD-1 agonist inhibits cell-mediated autoimmunity in pancreas tissue slices

靶向β细胞的PD-1激动剂抑制胰腺组织切片中的细胞介导的自身免疫

Becker, Matthew W; Brown, Matthew E; Wiseman, Katherine; Chiodetti, Ana Laura; Huber, Mollie K; Cuaycal, Alexandra E; Sintara, Pumin; Ferreira, Sandra M; Smurlick, Dylan; Barra, Jessie M; Ladd, Andrew M; Drotar, Denise M; Atkinson, Mark A; Weber, Peter; Al-Mossawi, Hussein; Russ, Holger A; Mahon, Tara M; Brusko, Todd M; Bossi, Giovanna; Phelps, Edward A

Genetic determinants of monocyte splicing are enriched for disease susceptibility loci

单核细胞剪接的遗传决定因素富集于疾病易感位点

Nassiri, Isar; Gilchrist, James J; Tong, Orion; Lau, Evelyn; Danielli, Sara; Mossawi, Hussein Al; Neville, Matthew J; Knight, Julian C; Fairfax, Benjamin P

Cell-targeted PD-1 agonists are potent NK-cell inhibitors

靶向细胞的PD-1激动剂是强效的NK细胞抑制剂。

Harriet C Pope ,Ana L Chiodetti ,Alice Newey ,Guillaume Rieunier ,David X Overton ,Eduardo Mateos-Diaz ,Tara M Mahon ,Giovanna Bossi ,Hussein Al-Mossawi ,Charlotte Viant

Metabolomic profiling of patients with lupus nephritis reveals unique metabolites that are modulated through type I interferon inhibition by anifrolumab treatment in a phase 2 trial

在一项二期临床试验中,对狼疮性肾炎患者进行代谢组学分析发现,阿尼弗鲁单抗治疗可通过抑制I型干扰素来调节独特的代谢物。

Gavin, Patrick G; Allman, Erik L; Jayne, David; Mysler, Eduardo; Amoura, Zahir; Di Poto, Cristina; Tian, Xiang; Hess, Sonja; Csomor, Eszter; Brohawn, Philip Z; Muthas, Daniel; Platt, Adam; Anzillotti, Consuelo; Stone, Heena; Seth, Asha; Woollard, Kevin; Al-Mossawi, Hussein; Lindholm, Catharina; Ferrari, Nicola

High prevalence of MASLD in psoriasis and psoriatic arthritis assessed with multiparametric magnetic resonance imaging

多参数磁共振成像评估显示,银屑病和银屑病关节炎患者中MASLD患病率较高

James, Lija; Diamond, Charlie; Al-Mossawi, Hussein; Andersson, Anneli; Pandya, Prashant; Shumbayawonda, Elizabeth; Izadi Firouzabadi, Leila; Watson, Lily; Savage, Laura J; Thomaides-Brears, Helena; Banerjee, Rajarshi; Coates, Laura C

Inhibition of cell-mediated immunity in type 1 diabetes by beta cell-targeted PD-1 agonists in pancreas tissue slices

胰腺组织切片中β细胞靶向PD-1激动剂对1型糖尿病细胞介导免疫的抑制作用

Becker, Matthew W; Brown, Matthew; Wiseman, Katherine; Chiodetti, Ana Laura; Huber, Mollie K; Cuaycal, Alexandra E; Sintara, Pumin; Ferreira, Sandra M; Smurlick, Dylan; Barra, Jessie M; Ladd, Andrew M; Drotar, Denise M; Atkinson, Mark A; Weber, Peter; Al-Mossawi, Hussein; Russ, Holger A; Mahon, Tara M; Brusko, Todd M; Bossi, Giovanna; Phelps, Edward A

Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials

在两项 3 期临床试验中,基因表达和蛋白质组学分析表明,使用阿尼弗鲁单抗阻断 I 型干扰素可调节系统性红斑狼疮患者的关键免疫病理通路。

Baker, Tina; Sharifian, Hoda; Newcombe, Paul J; Gavin, Patrick G; Lazarus, Mark N; Ramaswamy, Madhu; White, Wendy I; Ferrari, Nicola; Muthas, Daniel; Tummala, Raj; Morand, Eric F; Furie, Richard A; Vital, Edward M; Chamberlain, Chris; Platt, Adam; Al-Mossawi, Hussein; Brohawn, Philip Z; Csomor, Eszter

Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes

原代单核细胞中特定环境DNA甲基化的遗传决定因素的特征分析

James J Gilchrist ,Hai Fang ,Sara Danielli ,Marketa Tomkova ,Isar Nassiri ,Esther Ng ,Orion Tong ,Chelsea Taylor ,Dylan Muldoon ,Lea R Z Cohen ,Hussein Al-Mossawi ,Evelyn Lau ,Matt Neville ,Benjamin Schuster-Boeckler ,Julian C Knight ,Benjamin P Fairfax

Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor

在可溶性支架上展示 GPR65 胞外环的嵌合抗原,使得人们能够发现识别天然受体的抗体。

Barrett, Janine; Leysen, Seppe; Galmiche, Cécile; Al-Mossawi, Hussein; Bowness, Paul; Edwards, Thomas E; Lawson, Alastair D G

Correction: Targeting DORIS Remission and LLDAS in SLE: A Review

更正:针对系统性红斑狼疮的DORIS缓解和LLDAS:一项综述

Parra Sánchez, Agner R; van Vollenhoven, Ronald F; Morand, Eric F; Bruce, Ian N; Kandane-Rathnayake, Rangi; Weiss, Gudrun; Tummala, Raj; Al-Mossawi, Hussein; Sorrentino, Alessandro