Targeting the IL-36 receptor with spesolimab mitigates residual inflammation and prevents generalized pustular psoriasis flares
使用spesolimab靶向IL-36受体可减轻残留炎症并预防泛发性脓疱型银屑病发作。
期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI188530
Krueger, James G; Sarkar, Mrinal K; Lebwohl, Mark G; Morita, Akimichi; Gordon, Kenneth; Bogle, Rachael; Cole, Christopher; Coon, Anthony; Langley, Richard G; Warren, Richard B; Mostaghimi, Arash; Strober, Bruce; Burden, A David; Zheng, Min; Mangold, Aaron R; Anadkat, Milan J; Barker, Jonathan N; Merola, Joseph F; Tsoi, Lam C; Tang, Ming; Becker, Kolja; Delic, Denis; Thoma, Christian; Gudjonsson, Johann E