日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Longitudinal deep multi-omics profiling in a CLN3(Δex7/8) minipig model identifies biomarker signatures of disease

在CLN3(Δex7/8)小型猪模型中进行纵向深度多组学分析,鉴定出疾病的生物标志物特征。

Rechtzigel, Mitchell J; Lee, Brittany; Neville, Christine; Huang, Ting; Díaz, Ramón; Campos, Alex Rosa; Motamedchaboki, Khatereh; Hornburg, Daniel; Johnson, Tyler B; Swier, Vicki J; Weimer, Jill M; Brudvig, Jon J

Multiplexed Nanoparticle Protein Corona Enables Accurate and Precise Deep Plasma Proteomics

多重纳米颗粒蛋白冠可实现精确的深度血浆蛋白质组学分析

Huang, Ting; Wang, Jian; Stukalov, Alexey; Kreimer, Simion; Zhao, Xiaoyan; Cantrell, Lee S; Zhou, Xiaoyuan; Brewer, Adam; Ho, Giang; Murolo, Fredric; Quach, Kevin; Figa, Mike; Just, Seth; Castro, Gabriel; Elgierari, Eltaher; Benz, Ryan W; Motamedchaboki, Khatereh; Batzoglou, Serafim; Farokhzad, Omid C; Van Eyk, Jennifer E; Siddiqui, Asim

Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping

纳米颗粒富集质谱蛋白质组学可鉴定蛋白质改变变异体,用于精确的pQTL定位。

Suhre, Karsten; Venkataraman, Guhan Ram; Guturu, Harendra; Halama, Anna; Stephan, Nisha; Thareja, Gaurav; Sarwath, Hina; Motamedchaboki, Khatereh; Donovan, Margaret K R; Siddiqui, Asim; Batzoglou, Serafim; Schmidt, Frank

Protein Coronas on Functionalized Nanoparticles Enable Quantitative and Precise Large-Scale Deep Plasma Proteomics

功能化纳米颗粒上的蛋白质冠层可实现定量、精确的大规模深层血浆蛋白质组学分析

Huang, Ting; Wang, Jian; Stukalov, Alexey; Donovan, Margaret K R; Ferdosi, Shadi; Williamson, Lucy; Just, Seth; Castro, Gabriel; Cantrell, Lee S; Elgierari, Eltaher; Benz, Ryan W; Huang, Yingxiang; Motamedchaboki, Khatereh; Hakimi, Amirmansoor; Arrey, Tabiwang; Damoc, Eugen; Kreimer, Simion; Farokhzad, Omid C; Batzoglou, Serafim; Siddiqui, Asim; Van Eyk, Jennifer E; Hornburg, Daniel

Real-Time Search-Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

三混合质谱仪上的实时搜索辅助采集提高了多重单细胞蛋白质组学的覆盖率

Benjamin Furtwängler ,Nil Üresin ,Khatereh Motamedchaboki ,Romain Huguet ,Daniel Lopez-Ferrer ,Vlad Zabrouskov ,Bo T Porse ,Erwin M Schoof

Improved Single-Cell Proteome Coverage Using Narrow-Bore Packed NanoLC Columns and Ultrasensitive Mass Spectrometry

利用窄孔径填充纳米液相色谱柱和超灵敏质谱技术提高单细胞蛋白质组覆盖率

Cong, Yongzheng; Liang, Yiran; Motamedchaboki, Khatereh; Huguet, Romain; Truong, Thy; Zhao, Rui; Shen, Yufeng; Lopez-Ferrer, Daniel; Zhu, Ying; Kelly, Ryan T

Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment

人髓过氧化物酶 (hMPO) 在帕金森病患者的黑质神经元以及 hMPO-α-突触核蛋白-A53T 小鼠模型中均有表达,且与 α-突触核蛋白硝化和聚集增加以及运动障碍加剧相关。

Richard A Maki ,Michael Holzer ,Khatereh Motamedchaboki ,Ernst Malle ,Eliezer Masliah ,Gunther Marsche ,Wanda F Reynolds

Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases

泛素化依赖性寡聚化调节 Nedd4 连接酶的活性

Ilan Attali, William Sam Tobelaim, Avinash Persaud, Khatereh Motamedchaboki, Kobi J Simpson-Lavy, Bayan Mashahreh, Olga Levin-Kravets, Tal Keren-Kaplan, Inbar Pilzer, Martin Kupiec, Reuven Wiener, Dieter A Wolf, Daniela Rotin, Gali Prag

A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism

转录本特异性eIF3复合物介导能量代谢的全局翻译调控

Shah, Meera; Su, Dan; Scheliga, Judith S; Pluskal, Tomáš; Boronat, Susanna; Motamedchaboki, Khatereh; Campos, Alexandre Rosa; Qi, Feng; Hidalgo, Elena; Yanagida, Mitsuhiro; Wolf, Dieter A

p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity

变构抑制引起的 p97 组成变化被一种增加酶的 ATPase 活性的靶向机制抑制

Nam-Gu Her, Julia I Toth, Chen-Ting Ma, Yang Wei, Khatereh Motamedchaboki, Eduard Sergienko, Matthew D Petroski